. To estimate dose rates delivered by using radioactiveAu nanoparticles for prostate cancer nanobrachytherapy, identifying contribution by photons and electrons emmited from the source..
View Article and Find Full Text PDFPurpose: In this paper we present a further step in the implementation of a physical phantom designed to generate sets of "true" independent reference data as requested by TG-186, intending to address and mitigate the scarcity of experimental studies on brachytherapy (BT) validation in heterogeneous media. To achieve this, we incorporated well-known heterogeneous materials into the phantom in order to perform measurements of I dose distribution. The work aims to experimentally validate Monte Carlo (MC) calculations based on MBDCA and determine the conversion factors from LiF response to absorbed dose in different media, using cavity theory.
View Article and Find Full Text PDFPurpose: In this paper we present a phantom designed to provide conditions to generate set of "true" independent reference data as requested by TG-186, and mitigating the scarcity of experimental studies on brachytherapy validation. It was used to perform accurate experimental measurements of dose of I brachytherapy seeds using LiF dosimeters, with the objective of experimentally validating Monte Carlo (MC) calculations with model-based dose calculation algorithm (MBDCA). In addition, this work intends to evaluate a methodology to convert the experimental values from LiF into dose in the medium.
View Article and Find Full Text PDFModel-based dose calculation algorithms (MBDCAs) are the current tools to estimate dose in brachytherapy, which takes into account heterogeneous medium, therefore, departing from water-based formalism (TG-43). One aspect associated to MBCDA is the choice of dose specification medium since it offers two possibilities to report dose: (a) dose to medium in medium, D ; and (b) dose to water in medium, D . The discussion about the preferable quantity to be reported is underway.
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