Publications by authors named "Paula Cots-Rodriguez"
Fertilization involves the recognition and fusion of sperm and egg to form a previously unidentified organism. In mammals, surface molecules on the sperm and egg have central roles, and while adhesion is mediated by the IZUMO1-JUNO sperm-egg ligand-receptor pair, the molecule/s responsible for membrane fusion remain mysterious. Recently, MAIA/FCRL3 was identified as a mammalian egg receptor, which bound IZUMO1 and JUNO and might therefore have a bridging role in gamete recognition and fusion.
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- * Initially thought to consist of only three glycoproteins (ZP1, ZP2, ZP3) based on mouse studies, recent research indicates that ZP composition can vary significantly among different mammalian species due to evolutionary changes in the ZP gene family.
- * This review aims to compile recent findings on ZP composition and evolution, focusing on ZP biosynthesis, the specific roles of ZP proteins across species, and their interactions with other proteins in the reproductive environment.*
Ejaculated sperm are exposed to different environments before encountering the oocyte. However, how the sperm proteome changes during this transit remains unsolved. This study aimed to identify proteomic changes in boar sperm after incubation with male (seminal plasma, SP) and/or female (uterine fluid, UF; and oviductal fluid, OF) reproductive fluids.
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