[Serum Erythropoietin as Prognostic Marker in Myelodysplastic Syndromes].

Introduction: This myelodysplastic syndromes are a heterogeneous entity characterized by dysplasia, hypercellular bone marrow, cytopenias and risk of transformation to acute leukaemia. Prognostic factors, such as bone marrow fibrosis, lactate dehydrogenase and 2-microglobulin elevation have been described, but treatment is mainly based in the International Prognostic Scoring System.

Material And Methods: Our aim was to analyze serum's erythropoietin at diagnosis in de novo myelodysplastic syndromes patients, through its impact in overall survival and possible implementation as prognostic marker.

The Co-chaperone BAG2 Mediates Cold-Induced Accumulation of Phosphorylated Tau in SH-SY5Y Cells.

Inclusions of phosphorylated tau (p-tau) are a hallmark of many neurodegenerative disorders classified as "tauopathy," of which Alzheimer's disease is the most prevalent form. Dysregulation of tau phosphorylation disrupts neuron structure and function, and hyperphosphorylated tau aggregates to form neurotoxic inclusions. The abundance of ubiquitin in tau inclusions suggests a defect in ubiquitin-mediated tau protein degradation by the proteasome.

Wood, management and dust: analysis of the Context of Production of Goods and Services (CPGS) of an academic woodwork.

The CGPS of the woodwork of a public university was observed and analyzed. Apart from what is usual in the field of Ergonomics' studies, it is an academic context, where there is not a direct implication of profit, productivity and clientele. The group tried to sever negative and broadcasted opinions about the place by analyzing it from a different point of view.