[Cytogenetic analysis of material from spontaneous abortion].

Objective: To describe chromosomal abnormalities in spontaneous abortion material.

Methods: A retrospective compilation of karyotype analysis of slides stained with Band G was carried out by optical microscopy with materials of 428 abortion products referred for study.

Results: There were 145 normal results (33.

Effect of angiotensin II and losartan on the phagocytic activity of peritoneal macrophages from Balb/C mice.

Angiotensin II (AII), a product of rennin-angiotensin system, exerts an important role on the function of immune system cells. In this study, the effect of AII on the phagocytic activity of mouse peritoneal macrophages was assessed. Mice peritoneal macrophages were cultured for 48 h and the influence of different concentrations of AII (10(-14) to 10(-7) M) and/or losartan, 10(-16) to 10(-6) M), an AT1 angiotensin receptor antagonist, on phagocytic activity and superoxide anion production was determined.