Publications by authors named "Paula Alexandra Dos Santos Oliveira"
Mannose-binding lectin levels and MBL2 gene polymorphisms are associated with dengue infection in Brazilian children at the early ages.
Marília A Sena Priscila Mayrelle da Silva Castanha Ana Beatriz Giles Guimarães Paula Alexandra Dos Santos Oliveira Maria Almerice Lopes da Silva
Int J Infect Dis
April 2022
Background: The mannose-binding lectin (MBL) plays an important role in innate immunity. Genetically determined variations in serum levels of MBL may influence the susceptibility and clinical outcome of dengue infection in early life.
Methods: We investigated the MBL2 gene polymorphisms and serum levels of MBL (total and functional) in children with asymptomatic (n=17) and symptomatic (n=29) primary dengue infections and age-matched uninfected children (n=84) enrolled in a birth cohort with dengue in Brazil.