Publications by authors named "Paul W Estes"
Article Synopsis
- The Bio-Hermes Study aimed to create a database of blood-based and digital biomarkers to enhance the detection of Alzheimer's disease (AD) and mild cognitive impairment (MCI).
- The study involved 887 participants who were evaluated using Cognivue Clarity and amyloid PET scans, successfully differentiating between cognitively normal individuals, those with MCI, and probable AD with significant accuracy.
- Results indicated that Cognivue Clarity is effective in detecting cognitive impairments and could improve patient identification for treatment protocols and clinical trial recruitment.
World J Psychiatry
January 2020
Article Synopsis
- - The study aimed to identify cut-off scores for classifying cognitive impairment and to evaluate the safety and efficacy of a cognitive assessment tool, Cognivue, within a large validation study.
- - Two cohort studies were conducted with adults aged 55-95 at risk for cognitive decline, examining the alignment of Cognivue scores with a reference test called the St. Louis University Mental Status (SLUMS) through various statistical analyses.
- - Results indicated that specific Cognivue score ranges corresponded to cognitive impairment levels, with good agreement between Cognivue and SLUMS scores, and indicated reliability across multiple testing sessions.
