Metabolomic profiling and bactericidal effect of (Sonn.) Twaites. stem bark against methicillin-resistant .

The present study was carried out to establish the chemical profile of the methanolic extract of stem bark and investigate its antibacterial property against some human pathogenic bacteria. The extract was analysed using liquid and gas chromatography coupled to mass spectrometry. Antibacterial activity of extract against some human pathogenic bacteria was screened using the AlamarBlue method, and MIC and MBC were determined.

Chronic Gastric Ulcer Healing Actions of the Aqueous Extracts of Staple Plant Foods of the North-West, Adamawa, and West Regions of Cameroon.

Aim: This study is aimed at establishing phenolic compound profile and assessing the possible antiulcer activities of aqueous extracts of some staple plant foods from the West and North-West regions of Cameroon against chronic gastric ulcer models in rats.

Materials And Methods: Phenolic constituents of extracts were evaluated using HPLC-DAD. Aqueous extracts of , , , , "nkui" spices, and "yellow soup" spices were tested at two doses (200 and 400 mg/kg).

Antihistaminergic and Anticholinergic Properties of the Root Bark Aqueous Extract of (Ebenaceae) on Hypersecretion of Gastric Acid Induced in Wistar Rats.

Objective: The objective of this study was to elucidate the antisecretory mechanism of the root bark aqueous extract of (RBAEDM) in Wistar rats. . RBAEDM was tested on three experimental animal models of gastric acid hypersecretion including pyloric ligation (PL), PL with histamine, and carbachol pretreatments.

Eremomastax speciosa (Hochst.) Cufod. counteracts the delaying effect of indomethacin on Helicobacter pylori-associated chronic gastric ulcers healing.

Ethnopharmacological Relevance: Information collected from local traditional healers reported that Eremomastax speciosa (Hochst.) Cufod. has for a long time been used to manage gastric ulcers in many regions of Cameroon and beyond.

Antioxidant and Antifatigue Properties of the Aqueous Extract of Moringa oleifera in Rats Subjected to Forced Swimming Endurance Test.

The effects of the aqueous extract of Moringa oleifera on swimming performance and related biochemical parameters were investigated in male Wistar rats (130-132 g). Four groups of rats (16 per group) were fed a standard laboratory diet and given distilled water, 100, 200, or 400 mg/kg of extract, respectively, for 28 days. On day 28, 8 rats from each group were subjected to the forced swimming test with tail load (10% of body weight).

Effects of the dietary replacement of maize with sun-dried cocoa pods on the performance of growing rabbits.

Twenty seven mixed-breed growing rabbits (1.2-1.3 kg body weight) aged 10-12 weeks were used to study the effects of the dietary replacement of maize with sun-dried cocoa pod husks on the performance of growing rabbits in a 6-week trial.