Changes in serum leptin during phases of menstrual cycle of fertile women: relationship to age groups and fertility.

Background: It is established that serum level of leptin is affected by transitional phases of reproduction. It is also reported that the puberty is triggered when body fat and circulating levels of leptin exceed the critical thresholds, butthere is less focus on the serum level of leptin and its relationship with different phases of menstrual cycle and the fertility.

Objectives: The present study try to determines the serum concentration of leptin and fertility hormonesin the various phases of normal menstrual cycle of fertile women and compare any difference in serum concentration between age groups of 18-30 years and 31-41 years It is a well known fact that fertility start to decrease from age 31 years.

Low dose aspirin therapy and renal function in elderly patients.

Purpose: To determine whether low dose aspirin has any deleterious effects on renal function in elderly patients.

Methods: We conducted a prospective pilot study of 30 Nigerians older than 60 years with various chronic ailments necessitating the use of low dose aspirin. Patients gave their consent, and institutional ethical clearance was obtained.

Prevalence of anti-hepatitis C virus antibodies in pregnant women and their offspring in a tertiary hospital in Southwestern Nigeria.

Background: The aim of this prospective study was to determine the prevalence of HCV antibodies among pregnant women and their corresponding offspring in a tertiary medical centre in Southwestern Nigeria.

Method: Anti-HCV antibodies (anti-HCV antibodies) were analyzed in blood samples from mothers and cord samples from their corresponding offspring using the Enzyme Linked Immunosorbent Assay (ELISA) method. The results obtained from the study were expressed in simple percentages.