Chain-Extendable Crosslinked Hydrogels Using Branching RAFT Modification.

Functional crosslinked hydrogels were prepared from 2-hydroxyethyl methacrylate (HEMA) and acrylic acid (AA). The acid monomer was incorporated both via copolymerization and chain extension of a branching, reversible addition-fragmentation chain-transfer agent incorporated into the crosslinked polymer gel. The hydrogels were intolerant to high levels of acidic copolymerization as the acrylic acid weakened the ethylene glycol dimethacrylate (EGDMA) crosslinked network.

Constitutive Modelling of Polylactic Acid at Large Deformation Using Multiaxial Strains.

Sheet specimens of a PLLA-based polymer have been extended at a temperature near to the glass transition in both uniaxial and planar tension, with stress relaxation observed for some time after reaching the final strain. Both axial and transverse stresses were recorded in the planar experiments. In all cases during loading, yielding at small strain was followed by a drop in true stress and then strain hardening.

Flat broadband chaos generation in a discrete-mode laser subject to optical feedback.

Chaos generation in a discrete-mode (DM) laser subject to optical feedback is experimentally explored. The results show that a DM laser with only optical feedback can produce flat broadband chaos under an optimized feedback ratio. The effect of the laser bias current on the bandwidth and flatness of chaos is also investigated.

Electronic Health Record-Embedded Decision Support Platform for Morphine Precision Dosing in Neonates.

Morphine is the opioid most commonly used for neonatal pain management. In intravenous form, it is administered as continuous infusions and intermittent injections, mostly based on empirically established protocols. Inadequate pain control in neonates can cause long-term adverse consequences; however, providing appropriate individualized morphine dosing is particularly challenging due to the interplay of rapid natural physiological changes and multiple life-sustaining procedures in patients who cannot describe their symptoms.

Trait-based climate vulnerability assessments in data-rich systems: An application to eastern Bering Sea fish and invertebrate stocks.

Trait-based climate vulnerability assessments based on expert evaluation have emerged as a rapid tool to assess biological vulnerability when detailed correlative or mechanistic studies are not feasible. Trait-based assessments typically view vulnerability as a combination of sensitivity and exposure to climate change. However, in some locations, a substantial amount of information may exist on system productivity and environmental conditions (both current and projected), with potential disparities in the information available for data-rich and data-poor stocks.

Modelling the Mechanical and Strain Recovery Behaviour of Partially Crystalline PLA.

This is a study of the modelling and prediction of strain recovery in a polylactide. Strain recovery near the glass transition temperature is the underlying mechanism for the shape memory in an amorphous polymer. The investigation is aimed at modelling such shape memory behaviour.

The role of maternal age and context-dependent maternal effects in the offspring provisioning of a long-lived marine teleost.

Despite evidence of maternal age effects in a number of teleost species, there have been challenges to the assertion that maternal age intrinsically influences offspring quality. From an evolutionary perspective, maternal age effects result in young females paradoxically investing in less fit offspring despite a greater potential fitness benefit that might be gained by allocating this energy to individual somatic growth. Although a narrow range of conditions could lead to a maternal fitness benefit via the production of lower quality offspring, evolutionary theorists suggest these conditions are seldom met and that the reported maternal age effects are more likely products of the environmental context.

Broad tunable photonic microwave generation based on period-one dynamics of optical injection vertical-cavity surface-emitting lasers.

Photonic microwave generation based on period-one dynamics of an optically injected VCSEL has been study experimentally. The results have shown that the frequency of the generated microwave signal can be broadly tunable through the adjustment of the injection power and the frequency detuning. Strong optical injection power and higher frequency detuning are favorable for obtaining a high frequency microwave signal.

A Novel Diagnostic Aid for Detection of Intra-Abdominal Adhesions to the Anterior Abdominal Wall Using Dynamic Magnetic Resonance Imaging.

Introduction. Abdominal adhesions can cause serious morbidity and complicate subsequent operations. Their diagnosis is often one of exclusion due to a lack of a reliable, non-invasive diagnostic technique.

Reducing the cesarean delivery rates for breech presentations: administration of spinal anesthesia facilitates manipulation to cephalic presentation, but is it cost saving?

Background: External cephalic version (ECV) is infrequently performed and 98% of breech presenting fetuses are delivered surgically. Neuraxial analgesia can increase the success rate of ECV significantly, potentially reducing cesarean delivery rates for breech presentation. The current study aims to determine whether the additional cost to the hospital of spinal anesthesia for ECV is offset by cost savings generated by reduced cesarean delivery.

Towards radiological diagnosis of abdominal adhesions based on motion signatures derived from sequences of cine-MRI images.

This paper reports novel development and preliminary application of an image registration technique for diagnosis of abdominal adhesions imaged with cine-MRI (cMRI). Adhesions can severely compromise the movement and physiological function of the abdominal contents, and their presence is difficult to detect. The image registration approach presented here is designed to expose anomalies in movement of the abdominal organs, providing a movement signature that is indicative of underlying structural abnormalities.

Initial observations using a novel "cine" magnetic resonance imaging technique to detect changes in abdominal motion caused by encapsulating peritoneal sclerosis.

Encapsulating peritoneal sclerosis (EPS) is an uncommon complication of peritoneal dialysis (PD), with high mortality and morbidity. The peritoneum thickens, dysfunctions, and forms a cocoon that progressively "strangulates" the small intestine, causing malnutrition, ischemia, and infarction. There is as yet no reliable noninvasive means of diagnosis, but recent developments in image analysis of cine magnetic resonance imaging for the recognition of adhesions offers a way forward.

Combined antegrade and retrograde endoscopic retroperitoneal bypass of ureteric strictures: a modification of the 'rendezvous' procedure.

Objective: To evaluate our experience of treating complicated iatrogenic ureteric strictures with a combined antegrade and retrograde endoscopic retroperitoneal bypass technique, a modification of the so-called 'rendezvous' procedure.

Patients And Methods: Seven patients presented to our institution between 2004 and 2008 after developing a complicated iatrogenic ureteric stricture, impassable with solitary antegrade or retrograde stenting techniques. In most cases there was a significant loss of ureteric continuity, with some strictures of up to 10-12 cm.

Enhanced chaos synchronization in unidirectionally coupled vertical-cavity surface-emitting semiconductor lasers with polarization-preserved injection.

We experimentally study chaos synchronization in unidirectionally coupled vertical-cavity surface-emitting semiconductor lasers (VCSELs) with polarization-preserved and polarization-selected optical injection. The measurements show, in agreement with theoretical predictions, that the maximum cross coefficient of 0.884 obtained with polarization-preserved optical injection is significantly higher than the maximum cross coefficient of 0.

Isolation and characterisation of procyanidins from Rumex obtusifolius.

An acetone:water (7:3) extract obtained from the leaves of Rumex obtusifolius was fractionated into procyanidin oligomer and polymer fractions using a linear gradient and a simple step method on Sephadex LH-20. The chemical characteristics of the procyanidin fractions were studied by 13C-NMR spectroscopy, acid-catalysed degradation in the presence of benzyl mercaptan, matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) MS and electrospray ionisation (ESI) MS. The 13C-NMR showed that the polymer fraction consisted predominantly of procyanidin polymers, some with galloyl groups attached.

A framework for the modeling of gut blood flow regulation and postprandial hyperaemia.

After a meal the activity of the gut increases markedly as digestion takes place. Associated with this increase in activity is an increase in blood flow, which has been shown to be dependent on factors such as caloric content and constitution of the meal. Much qualitative work has been carried out regarding mechanisms for the presence of food in a section of gut producing increased blood flow to that section, but there are still many aspects of this process that are not fully understood.

Ureteric embolization: an alternative treatment strategy for urinary fistulae complicating advanced pelvic malignancy.

Objective: To report experience with a minimally invasive technique for palliation of urinary fistula/incontinence complicating advanced pelvic malignancy or its treatment.

Patients And Methods: We used ureteric embolization with permanent nephrostomy drainage in eight renal units in five patients for palliation of symptoms. All procedures were done under local anaesthesia as day-case procedures.

Experimental study of polarization switching of vertical-cavity surface-emitting lasers as a dynamical bifurcation.

We study the role of the bias current sweep rate in measurements of polarization switching (PS) of vertical-cavity surface-emitting lasers (VCSELs). We show that the polarization-resolved L-I (light-intensity) curve depends on the current sweep rate. As the current sweep rate increases, the PS occurs at higher bias currents for upward scans and at lower bias currents for downward scans.

Assessing the relationship between concentrations of malodor compounds and odor scores from judges.

Background: The purpose of this review was to assess the relationship between mean organoleptic scores (using a 0-to-5 scale) and concentrations of putative odorants representative of those thought to be important in oral malodor, as well as to propose a simple model that explains the dose-response curves obtained from a group of odor judges.

Methods: The model assumes that the scale is rooted at the detection threshold (0), the maximum score (5) is fully saturating and the brain and olfactory nervous system can act as a faithful transducer of the state of binding (occupancy) of the smell receptors in the nose. The authors predicted that the response would be exponential or sigmoidal in nature.

Suppression of polarization switching in vertical-cavity surface-emitting lasers by use of optical feedback.

The polarization properties of vertical-cavity surface-emitting lasers (VCSELs) subject to optical feedback are studied experimentally. It is thereby demonstrated that polarization-selective optical feedback can be utilized to entirely eliminate VCSEL polarization switching over the entire device operating range.

Synchronization of chaos in unidirectionally coupled vertical-cavity surface-emitting semiconductor lasers.

Synchronization of chaos is achieved experimentally in unidirectionally coupled external-cavity vertical-cavity surface-emitting semiconductor lasers operating in an open-loop regime. Synchronization is observed when the polarization of the transmitter is perpendicular to the polarization (x polarization) of the free-running receiver. The ratio of transmitter output to y-polarized receiver output power shows normal (positive-slope) synchronization.

Studies on the biosynthesis of phomoidride B (CP-263,114): evidence for a decarboxylative homodimerization pathway.

[reaction: see text]. Feeding experiments using a deuterium labeled C16 maleic anhydride and whole cell culture of ATCC 74256 led to the isolation of phomoidride B with deuterium incorporation at C(7) and C(19) as determined by 2H NMR and electrospray mass spectrometry. This result is in accord with a decarboxylative homodimerization of the C16 maleic anhydride as a key biosynthetic step leading to phomoidride B.