A novel activated-zinc antiseptic solution effective against MRSA and a pig model.

Objective: The purpose of this study was to investigate the antimicrobial efficacy of a novel activated zinc solution against meticillin-resistant (MRSA) and after one hour, and to evaluate any untoward effect of the solution on local wound tissue at 24 hours after solution exposure in a pig wound model.

Method: A pathogen-free, commercially raised, Yorkshire-cross female pig was acquired 12 days prior to the procedure. Within one week prior to the procedure, a small loopful of test bacteria, (pig-isolate) and MRSA (ATCC-6538), were streaked and cultured on a non-selective agar.

A Novel Activated Zinc Solution with Improved Efficacy Against Pseudomonas and MRSA Biofilm Compared to Chlorhexidine and Povidone-Iodine.

Introduction: The search for the optimal agent for infection eradication in periprosthetic joint infection (PJI) remains challenging as there are limited efficacious and safe options. The ideal solution should have significant bactericidal and anti-biofilm activity to be able to eradicate infection with the preservation of prosthetic components. Therefore, the purpose of this study was to 1) investigate the anti-biofilm efficacy of a novel activated zinc solution against Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA) biofilm in vitro and 2) compare its efficacy against two leading commercially available antimicrobial irrigants (CHG and 0.

The antimicrobial spectrum of Xeroform.

Introduction/background: Xeroform is a petrolatum-based fine mesh gauze containing 3% bismuth tribromophenate. Bismuth, similar to other metals, has antimicrobial properties. Xeroform has been used for decades in burn and plastic surgery as a donor site dressing and as a covering for wounds or partial thickness burns.