Publications by authors named "Paul Richard Scully"
Article Synopsis
- The study investigated the impact of wild-type transthyretin cardiac amyloidosis (ATTR) on patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI), identifying diagnostic and management challenges.
- Researchers analyzed data from 583 patients, comparing groups with AS, ATTR, AS-ATTR, and age-matched controls, assessing factors like cardiac remodeling and function using NT-proBNP as a main measurement.
- Results showed that patients with AS-ATTR experienced more severe cardiac issues compared to those with just AS, suggesting that the combined condition is at an early stage of amyloid infiltration, yet still resembles more advanced ATTR complications, indicating potential benefits from ATTR-targeted treatments.
