Publications by authors named "Paul Ndombo Koki"
Article Synopsis
- Mortality in children accounts for 15% of global AIDS-related deaths, with Cameroon facing a higher rate of 25%, mainly due to poor viral response.
- A study analyzed viral suppression (VS) among Cameroonian children and young adults receiving antiretroviral therapy (ART) to identify factors affecting VS, finding an overall rate of 82.3%.
- Key findings revealed that younger age, longer ART duration, and certain non-DTG-based regimens were independent predictors of non-VS, suggesting the need for prioritizing transition to DTG-based regimens to improve outcomes.
Viral suppression in the era of transition to dolutegravir-based therapy in Cameroon: Children at high risk of virological failure due to the lowly transition in pediatrics.
Medicine (Baltimore)
May 2023
This study aimed to compare viral suppression (VS) between children, adolescents, and adults in the frame of transition to dolutegravir (DTG)-based antiretroviral therapy (ART) in the Cameroonian context. A comparative cross-sectional study was conducted from January 2021 through May 2022 amongst ART-experienced patients received at the Chantal BIYA International Reference Centre in Yaounde-Cameroon, for viral load (VL) monitoring. VS was defined as VL < 1000 copies/mL and viral undetectability as VL < 50 copies/mL.
View Article and Find Full Text PDFFactors associated with non-adherence to antiretroviral therapy among HIV-infected adolescents aged 15-19 years: a snapshot from the Mother and Child Center in Yaounde, Cameroon.
Pan Afr Med J
October 2021
Introduction: non-adherence to antiretroviral therapy (ART) constitutes the main cause of therapeutic failure among HIV-infected adolescents, especially in the aged group 15 to 19 years. We aimed to determine factors associated with this non-adherence in this specific population.
Methods: we conducted a cross-sectional study at the Mother and Child Center in Yaounde from August to October 2018.
Dengue virus (DENV) causes a spectrum of diseases ranging from asymptomatic, mild febrile to a life-threatening illness: dengue hemorrhagic fever. The main clinical symptom of dengue is fever, similar to that of malaria. The prevalence of dengue virus infection, alone or in association with other endemic infectious diseases in children in Cameroon is unknown.
View Article and Find Full Text PDFBackground: We investigated HIV testing practices at baseline among pregnant women and their partners within a multicountry randomized trial aiming to evaluate the effect of enhanced prenatal posttest HIV counseling on men's involvement.
Methods: In Yaoundé, Cameroon, 484 pregnant women with stable partners were recruited on their first antenatal care visit. We analyzed the coverage of previous HIV testing among women and their partners and looked for the factors associated with previous HIV testing, using multivariable logistic regression.