Assessing the performance of a Loop Mediated Isothermal Amplification (LAMP) assay for the detection and subtyping of high-risk suptypes of Human Papilloma Virus (HPV) for Oropharyngeal Squamous Cell Carcinoma (OPSCC) without DNA purification.

Background: Oropharyngeal Squamous Cell Carcinoma (OPSCC) is increasing in incidence despite a decline in traditional risk factors. Human Papilloma Virus (HPV), specifically subtypes 16, 18, 31 and 35, has been implicated as the high-risk etiologic agent. HPV positive cancers have a significantly better prognosis than HPV negative cancers of comparable stage, and may benefit from different treatment regimens.

Technical note: Evaluation of tined endoscopically placed mucosal leads for temporary gastric neurostimulation.

Objective: To compare larger diameter corkscrew-tined leads with previously described intracardiac pacing leads for temporary gastric neurostimulation in a canine model.

Materials And Methods: Two mongrel dogs underwent gastroscopy under general anesthesia, with endoscopic placement of two cardiac leads (1 mm tine diameter, 4 mm depth) placed sequentially in 1) transverse configuration in the distal antrum mucosa; 2) longitudinal (1 cm apart) configuration in gastric corpus. Stomach was then stimulated with maximal parameters to induce neutrally mediated contraction.

Percutaneous endoscopically assisted transenteric full-thickness gastric biopsy: initial experience in humans.

Background: GI neuromuscular diseases (GINMD) can cause severe dysmotility and symptoms. Full-thickness biopsy specimens may help diagnose these disorders histologically.

Objective: To assess a novel percutaneous endoscopically assisted transenteric (PEATE) biopsy method for obtaining full-thickness gastric tissue in patients with suspected GINMD.