Objective: The study aims to analyze the utility of peri-operative systemic intravenous (IV) steroids in mitigating postoperative complications and improving clinical outcomes following anterior cervical discectomy and fusion (ACDF) surgery.
Methods: A systematic review was conducted by searching PubMed, Scopus, Cochrane, Web of Science, and Embase databases for studies assessing the role of IV or systemic steroids in ACDF surgery. Data extraction and risk of bias assessment were conducted independently by two reviewers using Covidence, with a third reviewer finalizing the data and settling any conflicts.