Publications by authors named "Paul Lorin Stoica"

Laparoscopic cholecystectomy (LC) is the gold standard treatment in acute cholecystitis. However, one in six cases is expected to be difficult due to intense inflammation and suspected adherence to and involvement of adjacent important structures, which may predispose patients to higher risk of vascular and biliary injuries. In this study, we aimed to identify the preoperative parameters with predictive value for surgical difficulties.

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Article Synopsis
  • The study evaluates how well certain blood ratios (NLR, PLR, SII) predict the severity and complications in acute calculous cholecystitis (AC) patients.
  • Out of these ratios, the neutrophil-to-lymphocyte ratio (NLR) was found to be the most effective for predicting advanced inflammation, with an optimal cut-off value of >4.19.
  • Additionally, high NLR levels were associated with complications post-surgery, while SII and PLR could also indicate systemic inflammatory responses.
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The incidence of common bile duct injuries following laparoscopic cholecystectomy (LC) remains three times higher than that following open surgery despite numerous attempts to decrease intraoperative incidents by employing better training, superior surgical instruments, imaging techniques, or strategic concepts. This paper is a narrative review which discusses from a contextual point of view the need to standardise the surgical approach in difficult laparoscopic cholecystectomies, the main strategic operative concepts and techniques, complementary visualisation aids for the delineation of anatomical landmarks, and the importance of cognitive maps and algorithms in performing safer LC. Extensive research was carried out in the PubMed, Web of Science, and Elsevier databases using the terms "difficult cholecystectomy", "bile duct injuries", "safe cholecystectomy", and "laparoscopy in acute cholecystitis".

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