Barriers to penicillin allergy de-labeling in the inpatient and outpatient settings: a qualitative study.

Background: Penicillin allergy is the most commonly reported drug allergy in the US. Despite evidence demonstrating that up to 90% of labels are incorrect, scalable interventions are not well established. As part of a larger mixed methods investigation, we conducted a qualitative study to describe the barriers to implementing a risk-based penicillin de-labeling protocol within a single site Veteran's hospital.

Feasibility of a pharmacy-led intervention to de-implement non-guideline-concordant proton pump inhibitor use.

Background: Proton pump inhibitors (PPIs) are among the most prescribed medications and are often used unnecessarily. PPIs are used for the treatment of heartburn and acid-related disorders. Emerging evidence indicates that PPIs are associated with serious adverse events, such as increased risk of Clostridioides difficile infection.

Continued Dosing of Oritavancin for Complicated Gram-Positive Infections.

Several retrospective and cohort analyses have suggested that continued dosing of oritavancin is both safe and efficacious for complicated Gram-positive infections, such as methicillin-resistant and vancomycin-resistant enterococci.

Antibiotic assessment at hospital discharge-Room for stewardship intervention.

Our stewardship team evaluated 19 months of discharge antibiotic prescriptions to determine prescribing appropriateness and to characterize the interventions made. Intervention occurred in 9.7% of patients, with a 58% acceptance rate.

Bone health evaluation in a veteran population: a need for the Fracture Risk Assessment Tool (FRAX).

Background: Approximately 2 million men in the United States have osteoporosis, but men are seldom evaluated or treated to prevent fracture. In the expanding veteran population, the fracture risk assessment tool, FRAX, could help reduce fracture risk. However, it is unknown how many veterans would meet the FRAX treatment threshold.

Patient assessment in the diagnosis, prevention, and treatment of osteoporosis.

Assessment of the patient with osteoporosis includes history and physical examination, laboratory testing, and imaging studies. Information gathered during this assessment assists clinicians in targeting strategies to prevent fractures. The medical history should contain items such as personal and family history of fractures, lifestyle, intake of substances such as vitamin D, calcium, corticosteroids, and other medications.

Chronic metoclopramide therapy for diabetic gastroparesis.

Objective: To review the safety and efficacy of chronic metoclopramide for diabetic gastroparesis.

Data Sources: Medical literature was accessed through MEDLINE (1965 to October 2002) and PubMed (1965 to October 2002). Key search terms included metoclopramide; diabetic gastroparesis; and dyskinesia, drug induced.

Acceptability of pharmacy-based bone density measurement by women and primary healthcare providers.

Objectives: To assess women's information sources regarding, and monetary value placed on, pharmacy-based bone density screening. In addition, we evaluated clinicians' response to peripheral bone mass measurements.

Design: We recruited 197 women 50 years of age or older in four rural Midwestern community pharmacies.