Publications by authors named "Paul Laeven"

Mass spectrometry imaging (MSI) is a technique that analyzes the chemical information and spatial distribution of surface analytes. Most MSI studies are conducted in microprobe mode, in which a mass spectrum is collected for each pixel to create a mass image. Thus, the spatial resolution, sample imaging area, and imaging speed are linked.

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Objectives: Reconstruction plates, used to bridge segmental defects of the mandible after tumor resection or traumatic bone tissue loss, are subjected to repeated stresses of mastication. High stress concentrations in these plates can result in hardware failure. Topology optimization (TO) could reduce the peak stress by computing the most optimal material distribution in a patient-specific implant (PSI) used for mandibular reconstruction.

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Article Synopsis
  • Bovine spongiform encephalopathy (BSE) caused big health and money problems in Europe in the 1980s and 90s, but now it's mostly under control thanks to research on prions (bad proteins) in animal food.
  • A European project called Priority worked from 2009 to 2014 to study prion diseases and helped create new rules to keep animals safe from these diseases.
  • The researchers believe it's really important to keep a ban on feeding certain animal proteins to other animals to prevent new kinds of prion diseases from spreading, since we still don't know a lot about them.
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Large skull bone defects resulting from craniotomies due to cerebral insults, trauma or tumours create functional and aesthetic disturbances to the patient. The reconstruction of large osseous defects is still challenging. A treatment algorithm is presented based on the close interaction of radiologists, computer engineers and cranio-maxillofacial surgeons.

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Background: Skull defects usually create aesthetic and functional disturbances to the patient. These defects are currently reconstructed by using computer-aided design and manufacturing processes. Classification of skull defects becomes important in discussing the complexity of reconstruction in clinical practice or comparing clinical results in scientific articles.

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