Classical Presentation of Disseminated Blastomycosis in a 44-Year-Old Healthy Man 3 Months After Diagnosis of COVID-19.

BACKGROUND During the COVID-19 pandemic, the incidence of opportunistic infections, including fungal infections, has increased. Blastomycosis is caused by inhalation of an environmental fungus, Blastomyces dermatides, which is endemic in parts of the USA and Canada. This case report is of a 44-year-old man from the American Midwest who presented with disseminated blastomycosis infection 3 months following a diagnosis of COVID-19.

Empowering medicine residents to order labs mindfully to improve patient-centered care.

Background: Unnecessary laboratory testing of hospitalized patients is prevalent.

Objective: We conducted a study focused on "mindful ordering" to decrease unnecessary laboratory ordering within an Internal Medicine residency program.

Designs, Settings And Participants: We collected survey data on resident/faculty perceptions of laboratory ordering as well as order information from the electronic medical record (EMR).

Matrix-enhanced secondary ion mass spectrometry (ME SIMS) using room temperature ionic liquid matrices.

Room temperature ionic liquids (ILs) have many applications including as matrices in MALDI. We wished to investigate the efficacy of ILs as matrices in time-of-flight secondary ion mass spectrometry and in mass spectrometric imaging (MS imaging). Two ILs derived from alpha-cyano-4-hydroxycinnamic acid (CHCA) were synthesized and tested using phospholipids, cholesterol, and peptides.