Deferoxamine-fibrin accelerates angiogenesis in a rabbit model of peripheral ischemia.

The intramuscular (i.m.) injection of a modified fibrin meshwork plus deferoxamine was tested in a rabbit model of acute hind-limb ischemia.

Direct fibrin injection to promote new collateral growth in hind limb ischemia in a rabbit model.

Unlabelled: Local stimulation of angiogenesis is a new approach for the treatment of critical limb ischemia. Our investigation tested intramuscular (i.m.