Surgeon Experience as a Risk Factor for Short-Term Failure for Ab Interno Gelatin Microstent: A Canadian Multicenter Propensity-Matched Study.

Purpose: To compare the efficacy and safety of early versus later ab interno gelatin microstent placement with mitomycin C.

Design: Canada-wide, multicenter, retrospective propensity score-matched cohort study.

Participants: Two hundred seventy eyes (135 early cases and 135 later cases) with no prior incisional surgery.

Tube Shunt Revision With Excision of Fibrotic Capsule Using Mitomycin C With and Without Ologen-a Collagen Matrix Implant: A 3-Year Follow-up Study.

Precis: Tube revision with capsule excision in failed glaucoma drainage devices (GDDs) has good medium-term success effectively reducing the intraocular pressure (IOP) and medication burden. Implantation of Ologen may limit the complications, particularly erosion.

Purpose: To evaluate the 36-month outcomes of tube shunt revision with capsule excision using Mitomycin C (MMC) versus MMC with Ologen-a collagen matrix implant.

Ab Interno Gel Implant-associated Bleb-related Infection.

Purpose: To examine the presentation and management of 3 cases of bleb-related infection following ab interno gel implant surgery, so as to add to the growing understanding of complications associated with the emerging landscape of newer, minimally invasive glaucoma surgical procedures, and how they are best managed.

Design: Multicenter retrospective interventional case series.

Methods: Consecutive cases of bleb-related infection following ab interno gel implant surgery from 2 university-affiliated hospitals were included.

The Ahmed Versus Baerveldt Study: Five-Year Treatment Outcomes.

Purpose: To compare 2 frequently used aqueous shunts for the treatment of glaucoma.

Design: International, multicenter, randomized trial.

Participants: Patients aged 18 years or older with uncontrolled glaucoma despite maximum tolerated medical therapy, many of whom had failed or were at high risk of failing trabeculectomy.

Mathematical Modeling of Outflow Facility Increase With Trabecular Meshwork Bypass and Schlemm Canal Dilation.

Purpose: To mathematically model the conventional aqueous humor outflow system with trabecular meshwork (TM) bypass and Schlemm canal (SC) dilation.

Methods: The SC was modeled as a rectangular channel with the TM modeled as a permeable membrane. The collector channels (CCs) were modeled as fluid sinks distributed along the outer wall of SC.

Gonioscopic findings associated with a positive dark-room provocative test in narrow angles after laser iridotomy.

Purpose: To determine clinical factors and ultrasound biomicroscopic (UBM) findings associated with a positive prone dark-room provocative test (DRPT) in patients with narrow angles after laser peripheral iridotomy (LPI).

Patients And Methods: Seventeen eyes with a positive DRPT and 18 eyes with a negative DRPT were included in this comparative case series, based on chart review of patients diagnosed with narrow angles persisting after LPI who had undergone clinical evaluation with a 45-minute DRPT and UBM imaging. Subjects with a positive DRPT [an increase of intraocular pressure (IOP) of 6 mm Hg or more] were compared with a negative DRPT control group.

Estimation of ocular rigidity in glaucoma using ocular pulse amplitude and pulsatile choroidal blood flow.

Purpose: Theoretical models and animal studies have suggested that scleral rigidity plays an important role in the pathogenesis of glaucoma. The aim of this study was to present a noninvasive technique for estimating ocular rigidity (E) in vivo, and to compare the estimated rigidity between patients with open-angle glaucoma (OAG); ocular hypertension (OHT); suspect glaucomatous disc (GS); and normal subjects (N). We hypothesized that OHT patients would have higher rigidity.

Anterior segment changes after pilocarpine and laser iridotomy for primary angle-closure suspects with Scheimpflug photography.

Purpose: To assess changes in Scheimpflug-based measurements of the anterior segment after pilocarpine administration and prophylactic laser peripheral iridotomy in narrow anterior chamber angles.

Methods: Thirty-seven eyes in 37 patients with occludable angles were included in this prospective interventional case series. Primary angle-closure suspects (iridotrabecular contact in 3 quadrants or more) were enrolled.

The Ahmed Versus Baerveldt study: one-year treatment outcomes.

Objective: To report the 1-year treatment outcomes of the Ahmed Versus Baerveldt (AVB) Study.

Design: Multicenter randomized clinical trial.

Participants: A total of 238 patients were enrolled in the study, including 124 in the Ahmed group and 114 in the Baerveldt group.

Combining rim area to disc area asymmetry ratio and Moorfields regression analysis of confocal scanning laser ophthalmoscopy for glaucoma screening.

Objective: To determine the utility of combining rim area to disc area asymmetry ratio (RADAAR) and Moorfields regression analysis (MRA) to detect primary open-angle glaucoma (POAG) using confocal scanning laser ophthalmoscopy (CSLO) (Heidelberg retina tomograph 3 (HRT3)) in high-risk populations.

Design: Cross-sectional study.

Participants: Subjects with high risk for developing POAG.

Screening for glaucoma with Moorfields regression analysis and glaucoma probability score in confocal scanning laser ophthalmoscopy.

Objective: To compare the validity of Moorfields regression analysis (MRA) and glaucoma probability score (GPS) of the confocal scanning laser ophthalmoscopy (Heidelberg retina tomograph 3; HRT3) in detecting glaucomatous optic nerve damage in a screening population.

Design: Population-based, cross-sectional study.

Participants: Subjects at high risk for development of open-angle glaucoma (OAG).

Assessment of factors affecting the difference in intraocular pressure measurements between dynamic contour tonometry and goldmann applanation tonometry.

Purpose: To determine if the difference in intraocular pressure (IOP) measurements between dynamic contour tonometry (DCT) and Goldmann applanation tonometry (GAT) is correlated with axial length (AL), and to assess the possible influence of age, sex, central corneal thickness (CCT), corneal hysteresis (CH), ocular pulse amplitude (OPA), and glaucoma status on the difference in IOP measurements between the 2 instruments (ΔIOP=DCTIOP- GATIOP).

Methods: Two hundred sixty-oneparticipants (509 eyes) in these 4 groups were included: 53 normal individuals (N; 106 eyes), 112 glaucoma patients (OAG; 212 eyes), 52 glaucoma suspects (GS; 103 eyes), and 44 patients with ocular hypertension (OHT; 88 eyes). The patients who had had an incisional ocular surgery were excluded.

The validity of screening for open-angle glaucoma in high-risk populations with single-test screening mode frequency doubling technology perimetry (FDT).

Purpose: To evaluate whether a single frequency doubling perimetry (FDT) test is a valid screening tool to detect open-angle glaucoma (OAG) in high-risk populations.

Patients And Methods: All participants underwent frequency doubling Technology perimetry (FDT C-20-5 algorithm, Carl Zeiss Meditec Inc, Dublin, CA) and complete ophthalmic examination. FDT printouts were classified according to Iwasaki and Patel protocols.

Angle closure glaucoma after angiography of carotid-cavernous fistula--a case report.

Acute angle closure glaucoma (AACG) is a rare complication of carotid-cavernous fistula (CCF). However, rarer is iatrogenic AACG subsequent to CCF's standard treatment, endovascular embolization. To our knowledge, this is the first case in which AACG after angiography (a failed attempt at embolization) is treated primarily with embolization, and the first case of AACG and CCF that has yielded such a successful visual recovery.

Racial variability of glaucoma risk factors between African Caribbeans and Caucasians in a Canadian urban screening population.

Background: The significance of race in the development and progression of glaucoma remains controversial, although in most cases the evidence shows greater prevalence and progression of the disease in African American populations. The purpose of this study was to determine the impact of the African Caribbean race on the variability of risk factors for glaucoma in an urban Canadian screening population.

Study Design: Population-based, cross-sectional study.

Determinants of adherence to glaucoma medical therapy in a long-term patient population.

Purpose: Estimate patient adherence to glaucoma medications and identify potential determinants of nonadherence.

Design: Descriptive study.

Methods: Two hundred patients with open angle glaucoma, ocular hypertension, or glaucoma suspects were interviewed regarding their glaucoma and its treatment and their charts were reviewed.

Chronic angle-closure glaucoma secondary to a suprachoroidal effusion induced by central retinal vein occlusion.

A 68-year-old woman presented to the ophthalmology emergency clinic with a painful left eye of a few hours' duration. One month prior, the patient had presented with a central retinal vein occlusion in the same eye. Examination revealed an intraocular pressure of 32 mm Hg in the left eye with 360 degree angle closure unaltered by indentation, a patent iridectomy from a previous combined phacoemulsification and trabeculectomy surgery, and no evident iris or angle neovascularization.

Relationship between travoprost and central corneal thickness in ocular hypertension and open-angle glaucoma.

Purpose: To evaluate whether treatment with travoprost, an F2a prostaglandin analog, affects central corneal thickness (CCT) and whether intraocular pressure (IOP) response to the medication is related to baseline CCT.

Methods: This was a prospective, interventional, nonrandomized, nonconsecutive, clinical trial. In this multicenter study, 379 total patients, 220 with newly or previously diagnosed open-angle glaucoma (OAG), 141 with ocular hypertension (OHT), and 18 unspecified, were recruited from 15 Canadian sites.

Validity of screening for glaucomatous optic nerve damage using confocal scanning laser ophthalmoscopy (Heidelberg Retina Tomograph II) in high-risk populations: a pilot study.

Purpose: To evaluate whether confocal scanning laser ophthalmoscopy (Heidelberg Retina Tomograph II [HRT II], Heidelberg Engineering, Heidelberg, Germany) is a valid tool for the detection of glaucomatous optic nerve damage.

Design: Observational, cross-sectional, nonconsecutive study in Montreal, Canada.

Participants: Three hundred three nonconsecutive, high-risk persons were enrolled during a 6-month period.

Selective laser trabeculoplasty (SLT) complicated by intraocular pressure elevation in eyes with heavily pigmented trabecular meshworks.

Purpose: To report and assess the complication of intraocular pressure (IOP) elevations after selective laser trabeculoplasty (SLT) in patients with heavily pigmented trabecular meshworks.

Design: Noncomparative, observational case series.

Methods: Retrospective analysis of the medical files of four glaucoma patients with heavily pigmented trabecular meshwork, who presented with IOP elevations after SLT.

Phacoemulsification and goniosynechialysis in the management of unresponsive primary angle closure.

Purpose: To evaluate the effectiveness of phacoemulsification and goniosynechialysis (PEGS) in managing acute and subacute primary angle closure unresponsive to conventional therapy.

Materials And Methods: Retrospective series of patients of six glaucoma-trained surgeons with primary angle closure that did not respond to medical management, Nd:YAG laser peripheral iridotomy, or argon laser peripheral iridoplasty.

Results: A total of twenty-one patients with an average age of 65.

Thrombocytopenia and the risks of intraocular surgery.

Background And Objective: In thrombocytopenia, a hemorrhagic diathesis is usually present due to a low platelet count and has been related to the development of cataracts and retinopathy. The concomitant administration of nonsteroidal anti-inflammatory drugs can increase the hemorrhagic diathesis. The purpose of this study was to investigate the impact of thrombocytopenia during and after intraocular surgery.

Ultrasound biomicroscopy and management of late posterior migration of a ripcord suture after glaucoma drainage implant surgery.

Three years after receiving a Baerveldt tube implant for neovascular glaucoma, a 50-year-old man presented to the Wills Eye Hospital Glaucoma Service with pain and decreased vision in his left eye. On examination, a 4-0 nylon ripcord suture was seen to have migrated posteriorly through the pupil and in front of the intraocular lens. The distal end of the suture was not seen on dilated indirect ophthalmoscopic examination or by standard B-scan ultrasonography.