Publications by authors named "Paul J Duic"
Background: Recurrent glioblastoma (rGBM) has limited treatment options. This phase 1 protocol was designed to study the safety and preliminary efficacy of TPI 287, a central nervous system penetrant microtubule stabilizer, in combination with bevacizumab (BEV) for the treatment of rGBM.
Methods: GBM patients with up to 2 prior relapses without prior exposure to anti-angiogenic therapy were eligible.