Mapping the effects of ozone pollution and mixing on floral odour plumes and their impact on plant-pollinator interactions.

The critical ecological process of animal-mediated pollination is commonly facilitated by odour cues. These odours consist of volatile organic compounds (VOCs), often with short chemical lifetimes, which form the strong concentration gradients necessary for pollinating insects to locate a flower. Atmospheric oxidants, including ozone pollution, may react with and chemically alter these VOCs, impairing the ability of pollinators to locate a flower, and therefore the pollen and nectar on which they feed.

Improving patient diary use in intensive care: A quality improvement report.

Background: Patients surviving critical illness are at risk of developing psychological symptoms that affect quality of life and recovery. Patient diaries may improve psychological outcomes by reducing gaps in memory and contextualising what has happened during admission. Factors including lack of guidelines, lack of awareness and time constraints may lead to poor diary use.

Improving resuscitation decisions: a trust-wide initiative.

Introduction: Treatment escalation plans (TEPs) are important to ensure that every patient has their ceiling of care discussed and documented formally. At Medway Foundation Trust, we introduced TEP forms in September 2016 which are to be completed by the relevant consultant within 24 hours of admission.

Aims And Methods: To evaluate whether TEP forms had been effective at improving escalation planning and whether they had a subsequent impact in do not attempt cardiopulmonary resuscitation (DNACPR) decision-making.

Scalar Fluxes Near a Tall Building in an Aligned Array of Rectangular Buildings.

Scalar dispersion from ground-level sources in arrays of buildings is investigated using wind-tunnel measurements and large-eddy simulation (LES). An array of uniform-height buildings of equal dimensions and an array with an additional single tall building (wind tunnel) or a periodically repeated tall building (LES) are considered. The buildings in the array are aligned and form long streets.

Wind-Tunnel Simulation of Weakly and Moderately Stable Atmospheric Boundary Layers.

The simulation of horizontally homogeneous boundary layers that have characteristics of weakly and moderately stable atmospheric flow is investigated, where the well-established wind engineering practice of using 'flow generators' to provide a deep boundary layer is employed. Primary attention is given to the flow above the surface layer, in the absence of an overlying inversion, as assessed from first- and second-order moments of velocity and temperature. A uniform inlet temperature profile ahead of a deep layer, allowing initially neutral flow, results in the upper part of the boundary layer remaining neutral.

Mean and turbulent mass flux measurements in an idealised street network.

Pollutant mass fluxes are rarely measured in the laboratory, especially their turbulent component. They play a major role in the dispersion of gases in urban areas and modern mathematical models often attempt some sort of parametrisation. An experimental technique to measure mean and turbulent fluxes in an idealised urban array was developed and applied to improve our understanding of how the fluxes are distributed in a dense street canyon network.

Immersive visualization for enhanced computational fluid dynamics analysis.

Modern biomedical computer simulations produce spatiotemporal results that are often viewed at a single point in time on standard 2D displays. An immersive visualization environment (IVE) with 3D stereoscopic capability can mitigate some shortcomings of 2D displays via improved depth cues and active movement to further appreciate the spatial localization of imaging data with temporal computational fluid dynamics (CFD) results. We present a semi-automatic workflow for the import, processing, rendering, and stereoscopic visualization of high resolution, patient-specific imaging data, and CFD results in an IVE.

Engineered DNA ligases with improved activities in vitro.

The DNA ligase from bacteriophage T4 is one of the most widely used enzymes in molecular biology. It has evolved to seal single-stranded nicks in double-stranded DNA, but not to join double-stranded fragments with cohesive or blunt ends. Its poor activity in vitro, particularly with blunt-ended substrates, can lead to failed or sub-optimal experimental outcomes.

Minimising delays in commencing therapeutic hypothermia after out-of-hospital cardiac arrest: the importance of a multi-disciplinary team approach.

Therapeutic hypothermia (TH) is now a well established therapy in resuscitation guidelines. We retrospectively analysed our first 18 months' data for all patients who underwent TH for out-of-hospital cardiac arrest (OHCA), measuring delays incurred during each patient episode, safety, and ICU outcomes. Sixteen patients received TH for OHCA.