Publications by authors named "Paul Greillier"
Article Synopsis
- High-intensity focused ultrasound (HIFU) is a new treatment for cardiac arrhythmias that creates lesions deep within heart tissue.
- This study uses numerical modeling to simulate the effects of HIFU on heart models that can move and deform, focusing on two key areas: the atrioventricular node and ventricular apex.
- Results show that motion and deformation significantly affect the treatment duration and lesion characteristics, indicating the need for precise modeling in developing effective HIFU strategies.
Described here is a study of transesophageal thermal ablation of isolated and perfused beating hearts and non-human primates. An endoscope integrating a transesophageal echocardiography probe and a high-intensity focused ultrasound transducer was built and tested on five Langendorff-isolated hearts and three 30-kg baboons. B-Mode ultrasound, passive elastography and magnetic resonance imaging were performed to monitor thermal lesions.
View Article and Find Full Text PDFCatheter ablation for the treatment of arrhythmia is associated with significant complications and often-repeated procedures. Consequently, a less invasive and more efficient technique is required. Because high-intensity focused ultrasound (HIFU) enables the generation of precise thermal ablations in deep-seated tissues without harming the tissues in the propagation path, it has the potential to be used as a new ablation technique.
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