Publications by authors named "Paul G Bos"
Article Synopsis
- Basal cell carcinomas (BCCs) that leave positive tumor margins after excision have a higher chance of recurring, making complete removal crucial during treatment.
- The study assessed the reliability of the Whole Specimen Intraoperative Frozen Section Analysis (WIFSA) technique by comparing it to the standard postoperative analysis in over a thousand BCC cases and tracking recurrence rates for up to 10 years.
- Results showed that WIFSA had a 98.8% agreement with postoperative analysis and a low recurrence rate of 2.1% in BCCs with a tumor-free margin after an average follow-up of 5.6 years.
Background And Objectives: We excised cutaneous squamous cell carcinoma (cSCC) of the face while using intra-operative frozen section analysis of the margins in an optimized bread-loafing fashion (WIFSA).
Methods: Medical records were reviewed of 160 cSCCs of the face that were treated by surgical excision with WIFSA between April 2007 and January 2013. The accuracy of WIFSA was verified by comparing results with postoperative formalin-fixed paraffin-embedded (FFPE) sections.