Publications by authors named "Paul F Sowman"

Article Synopsis
  • Computational neurosurgery combines artificial intelligence and computational modeling to enhance the diagnosis and treatment of neurosurgical conditions, aiming to advance clinical neurosciences.
  • The field seeks to integrate ethical considerations to ensure that the use of AI is conducted responsibly and prioritizes patient care, ultimately aiming to prevent errors in treatment.
  • This initiative serves as a guide for practitioners, ethicists, and scientists in the application of ethical standards within computational neurosurgery.
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Predictive coding has emerged as a prominent theoretical framework for understanding perception and its neural underpinnings. There has been a recent surge of interest in the predictive coding framework across the mind sciences. However, comparatively little of the research in this field has investigated the neural underpinnings of predictive coding in young neurotypical and autistic children.

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Estimating intracranial current sources underlying the electromagnetic signals observed from extracranial sensors is a perennial challenge in non-invasive neuroimaging. Established solutions to this inverse problem treat time samples independently without considering the temporal dynamics of event-related brain processes. This paper describes current source estimation from simultaneously recorded magneto- and electro-encephalography (MEEG) using a recurrent neural network (RNN) that learns sequential relationships from neural data.

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Neuroimaging research requires purpose-built analysis software, which is challenging to install and may produce different results across computing environments. The community-oriented, open-source Neurodesk platform ( https://www.neurodesk.

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. To use a recurrent neural network (RNN) to reconstruct neural activity responsible for generating noninvasively measured electromagnetic signals..

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In the current article, we examined the flutter-duration illusion; the extension of perceived duration when an interval is filled with auditory flutter. Participants reproduced flutter-filled and empty durations while electrophysiological activity was recorded. As expected, participants over-produced durations when they were filled with auditory flutter rather than unfilled.

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Neuroimaging data analysis often requires purpose-built software, which can be challenging to install and may produce different results across computing environments. Beyond being a roadblock to neuroscientists, these issues of accessibility and portability can hamper the reproducibility of neuroimaging data analysis pipelines. Here, we introduce the Neurodesk platform, which harnesses software containers to support a comprehensive and growing suite of neuroimaging software (https://www.

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There is mounting evidence for predictive coding theory from computational, neuroimaging, and psychological research. However, there remains a lack of research exploring how predictive brain function develops across childhood. To address this gap, we used pediatric magnetoencephalography to record the evoked magnetic fields of 18 younger children (M = 4.

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Event-related potential (ERP) sensitivity to faces is predominantly characterized by an N170 peak that has greater amplitude and shorter latency when elicited by human faces than images of other objects. We aimed to develop a computational model of visual ERP generation to study this phenomenon which consisted of a three-dimensional convolutional neural network (CNN) connected to a recurrent neural network (RNN).The CNN provided image representation learning, complimenting sequence learning of the RNN for modeling visually-evoked potentials.

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Episodic memory deficits are a common consequence of aging and are associated with a number of neurodegenerative disorders (e.g., Alzheimer's disease).

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In cognitive neuroscience research, computational models of event-related potentials (ERP) can provide a means of developing explanatory hypotheses for the observed waveforms. However, researchers trained in cognitive neurosciences may face technical challenges in implementing these models. This paper provides a tutorial on developing recurrent neural network (RNN) models of ERP waveforms in order to facilitate broader use of computational models in ERP research.

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Article Synopsis
  • The study used magnetoencephalography (MEG) and fast periodic visual stimulation (FPVS) to explore how both children and adults respond to morphemes in words.
  • Participants saw rapid streams of base stimuli mixed with 'oddball' stimuli (like familiar words) to measure neural responses to morphological structures.
  • Results indicated that while developing readers (children) showed a central occipital response for identifying stems, skilled readers (adults) had a more left-side response for identifying suffixes, highlighting differences in morpheme processing maturity between the two groups.
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Background: Gilles de la Tourette Syndrome (GTS) is a childhood-onset neuropsychiatric disorder characterised by motor and vocal tics. While Comprehensive Behavioural Intervention for Tics (CBIT) is an effective, non-pharmacological treatment for patients with GTS, the underlying neurophysiological basis of this intervention has not been investigated.

Methods: To investigate the clinical effectiveness of CBIT in reducing tic severity in young people with GTS and explore neurophysiological mechanisms associated with clinical change.

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Visual snow refers to the persistent visual experience of static in the whole visual field of both eyes. It is often reported by patients with migraine and co-occurs with conditions such as tinnitus and tremor. The underlying pathophysiology of the condition is poorly understood.

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Bilinguals are known to switch language spontaneously in everyday conversations, even if there are no external requirements to do so. However, in the laboratory setting, language control is often investigated using forced switching tasks, which result in significant performance costs. The present study assessed whether switching would be less costly when performed in a more natural fashion, and what factors might account for this.

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Stuttering is a neurodevelopmental speech disorder characterized by the symptoms of speech repetition, prolongation, and blocking. Stuttering-related dysfluency can be transiently alleviated by providing an external timing signal such as a metronome or the voice of another person. Therefore, the existence of a core motor timing deficit in stuttering has been speculated.

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Functional near-infrared spectroscopy (fNIRS) is an increasingly popular tool in auditory research, but the range of analysis procedures employed across studies may complicate the interpretation of data. We aim to assess the impact of different analysis procedures on the morphology, detection, and lateralization of auditory responses in fNIRS. Specifically, we determine whether averaging or generalized linear model (GLM)-based analysis generates different experimental conclusions when applied to a block-protocol design.

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Article Synopsis
  • A study explored how bilingual speakers select the appropriate language using two levels of inhibitory control: whole-language and item-specific.
  • The researchers introduced univalent (same language) and bivalent (different languages) stimuli in a cued language switching task to measure these levels of control.
  • Neuroimaging indicated that the pre-supplementary motor area (pre-SMA) is activated during language switching, but TMS results showed it plays a key role in general speech execution, with mixed evidence for its specific involvement in either level of inhibition.
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Age-related decline in motor function is associated with over-activation of the sensorimotor circuitry. Using a multimodal MEG-fMRI paradigm, we investigated whether this neural over-recruitment in old age would be related to changes in movement-related beta desynchronization (MRBD), a correlate of the inhibitory neurotransmitter γ-aminobutyric acid (GABA), and whether it would characterize compensatory recruitment or a reduction in neural specialization (dedifferentiation). We used MEG to assess age-related changes in beta band oscillations in primary motor cortices, fMRI to localize age-related changes in brain activity, and the Finger Configuration Task to measure task performance during overt and covert motor processing: motor execution (ME) and motor imagery (MI).

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Speech-induced suppression is the normal, relative amplitude reduction of the auditory evoked potential for self-, compared to externally-generated, auditory stimulation. It remains controversial as to whether adults who stutter exhibit expected auditory modulation during speech; some studies have reported a significant difference between stuttering and fluent groups in speech-induced suppression during speech movement planning, while others have not. We compared auditory evoked potentials (N1 component) for auditory feedback arising from one's own voice (Speaking condition) with passive listening to a recording of one's own voice (Listening condition) in 24 normally-fluent speakers and 16 adults who stutter under various delayed auditory feedback (DAF) time conditions (100 ms, 200 ms, 500 ms, and 1,000 ms).

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Bilinguals have a remarkable ability to juggle two languages. A central question in the field is concerned with the control mechanisms that enable bilinguals to switch language with ease. Theoretical models and neuroimaging evidence suggest that a range of control processes are at play during language switching, and their underlying neural mechanisms are closely related to executive function.

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Many aspects of an event can change perceived duration. A common example of this is the magnitude-duration illusion, in which a high magnitude (e.g.

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A growing literature conceptualises typical brain development from a network perspective. However, largely due to technical and methodological challenges inherent in paediatric functional neuroimaging, there remains an important gap in our knowledge regarding the typical development of functional brain networks in "preschool" childhood (i.e.

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Magnetoencephalography (MEG) is a non-invasive neuroimaging technique which directly measures magnetic fields produced by the electrical activity of the human brain. MEG is quiet and less likely to induce claustrophobia compared with magnetic resonance imaging (MRI). It is therefore a promising tool for investigating brain function in young children.

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