Publications by authors named "Paul Escher"
Objectives/hypothesis: Patients with cleft lip and/or palate (CLP) are at increased risk of malnutrition. Acute and chronic malnutrition have been associated with elevated risk of postsurgical wound complications, adding morbidity and cost to patients and their families. To study the association between demographic factors, including insurance type, race, and median neighborhood income (MNI), and malnutrition in patients with CLP.
View Article and Find Full Text PDFObjectives/hypothesis: To assess the prevalence of acute and chronic malnutrition at the time of surgery in patients with cleft lip and/or palate (CLP) at our institution, and to quantify nutrition as a risk factor for postsurgical complications following CLP surgery.
Study Design: Retrospective cohort study.
Methods: Retrospective review of 855 children undergoing initial cleft lip or palate surgery, or revision surgery after fistula/dehiscence of initial cleft repair.
Background: Peroxisome proliferator-activated receptor-gamma (PPAR-γ) activators have anti-cancer effects. Our objective was to determine the effect of PPAR-γ ligands 15-deoxy-D -Prostaglandin J (15-PGJ ) and ciglitazone on proliferation, apoptosis, and NF-κB in human oral squamous cell carcinoma cell lines.
Methods: NA and CA9-22 cells were treated in vitro with 15-PGJ and ciglitazone.
Article Synopsis
- The study assessed the impact of a preoperative protocol using erythropoietin (EPO) and ferrous sulfate, alongside tranexamic acid (TXA), on blood transfusion requirements in patients with craniosynostosis undergoing surgery.
- A retrospective analysis was conducted on 36 patients, comparing outcomes between a control group (pre-2014, receiving standard blood transfusions) and a study group (post-2014, following the new protocol).
- Results showed the study group had significantly higher preoperative hemoglobin levels, lower intraoperative transfusion rates, and no postoperative transfusions, indicating the protocol effectively reduced the need for blood transfusions during and after surgery.
Basaloid squamous cell carcinoma (BSCC) with a spindle cell component of the head and neck is an uncommon entity. In this case, we present a radiology-pathology correlation of a rare laryngeal BSCC with sarcomatous transformation and osteosarcomatous differentiation involving the laryngeal cartilage, which thus mimicked clinically and radiographically osteosarcoma or chondrosarcoma with calcification. Microscopic examination revealed predominantly BSCC with extensive osseous metaplasia among sheets and nests of basaloid tumor cells.
View Article and Find Full Text PDFPurpose: To assess the success of a protocol using preoperative erythropoietin (EPO) and iron with perioperative tranexamic acid (TXA) in reducing blood transfusion in sagittal craniosynostosis surgery.
Methods: A retrospective chart review of all sagittal craniosynostosis patients undergoing open repair at our institution since 2010 was conducted. A novel protocol of preoperative EPO with iron and perioperative TXA, along with a shift away from automatic transfusion, was initiated in 2014.
Introduction: Indwelling inferior vena cava (IVC) filters are associated with complications, and the US Food and Drug Administration recommends their prompt removal when no longer indicated. Therefore, assessing strategies for increasing retrieval rates is warranted.
Objective: To analyze the variability of IVC filter retrieval rates within our institution based on 2 separate, pre-existing processes in which IVC retrieval is planned for before or after hospital discharge.