Upstream Oil and Gas Production and Community COVID-19 Case and Mortality Rates in California, USA.

Higher concentrations of ambient air pollutants, including PM and NO, and other pollutants have been found near active oil and gas wells and may be associated with adverse COVID-19 outcomes. We assessed whether residential exposure to nearby oil and gas production was associated with higher rates of the respiratory infection COVID-19 and related mortality using a population-based ecological study in California. Using gridded population estimates, we estimated area-level exposure to annual average oil and gas production volume from active wells within 1 kilometer (km) of populated areas within census block groups from 2018 to 2020.

Estimated human intake of endogenous and exogenous hormones from beef in the United States.

Background: Endogenous and exogenous hormones may be present in beef. Human consumption of hormones has been linked to adverse health effects.

Objective: To estimate daily intake of hormonal growth promotants (HGP) from beef consumed by the US population.

Per- and polyfluoroalkyl substances (PFAS) in drinking water in Southeast Los Angeles: Industrial legacy and environmental justice.

Per- and polyfluoroalkyl substances (PFAS) are persistent chemicals of increasing concern to human health. PFAS contamination in water systems has been linked to a variety of sources including hydrocarbon fire suppression activities, industrial and military land uses, agricultural applications of biosolids, and consumer products. To assess PFAS in California tap water, we collected 60 water samples from inside homes in four different geographic regions, both urban and rural.

Cohort profile: The Assessing Imperial Valley Respiratory Health and the Environment (AIRE) study.

Background: The Children's Assessing Imperial Valley Respiratory Health and the Environment (AIRE) study is a prospective cohort study of environmental influences on respiratory health in a rural, southeastern region of California (CA), which aims to longitudinally examine the contribution of a drying saline lake to adverse health impacts in children.

Objectives: This cohort was established through a community-academic partnership with the goal of assessing the health effects of childhood exposures to wind-blown particulate matter (PM) and inform public health action. We hypothesize that local PM sources are related to poorer children's respiratory health.

Association between long-term exposure to particulate air pollution with SARS-CoV-2 infections and COVID-19 deaths in California, U.S.A.

Previous studies have reported associations between air pollution and COVID-19 morbidity and mortality, but most have limited their exposure assessment to a large area, have not used individual-level variables, nor studied infections. We examined 3.1 million SARS-CoV-2 infections and 49,691 COVID-19 deaths that occurred in California from February 2020 to February 2021 to evaluate risks associated with long-term neighborhood concentrations of particulate matter less than 2.

Returning Individual Tap Water Testing Results to Research Study Participants after a Wildfire Disaster.

After the devastating wildfire that destroyed most of the town of Paradise, California in 2018, volatile organic compounds were found in water distribution pipes. Approximately 11 months after the fire, we collected tap water samples from 136 homes that were still standing and tested for over 100 chemicals. Each participant received a customized report showing the laboratory findings from their sample.

Fire and Water: Assessing Drinking Water Contamination After a Major Wildfire.

We investigated patterns of volatile organic compound (VOC) contamination in drinking water systems affected by the California 2018 Camp Fire. We performed spatial analysis of over 5000 water samples collected over a 17 month period by a local water utility, sampled tap water for VOCs in approximately 10% ( = 136) of standing homes, and conducted additional nontargeted chemical analysis of 10 samples. Benzene contamination was present in 29% of service connections to destroyed structures and 2% of service connections to standing homes.

Performance of a Low-Cost Sensor Community Air Monitoring Network in Imperial County, CA.

Air monitoring networks developed by communities have potential to reduce exposures and affect environmental health policy, yet there have been few performance evaluations of networks of these sensors in the field. We developed a network of over 40 air sensors in Imperial County, CA, which is delivering real-time data to local communities on levels of particulate matter. We report here on the performance of the Network to date by comparing the low-cost sensor readings to regulatory monitors for 4 years of operation (2015-2018) on a network-wide basis.

Developing Youth Environmental Health Literacy and Civic Leadership through Community Air Monitoring in Imperial County, California.

With a rapidly changing climate, new leaders must be trained to understand and act on emerging environmental threats. In California's Imperial Valley, a collaborative of community members, researchers, and scientists developed a community air monitoring network to provide local residents with better air quality information. To expand the reach of the project and to prepare the next generation of youth leaders we developed an internship program to increase environmental health literacy and civic leadership.

Community-Engaged Air Monitoring to Build Resilience Near the US-Mexico Border.

Initiated in response to community concerns about high levels of air pollution and asthma, the Imperial County Community Air Monitoring Project was conducted as a collaboration between a community-based organization, a non-governmental environmental health program, and academic researchers. This community-engaged research project aimed to produce real-time, community-level air quality information through the establishment of a community air monitoring network (CAMN) of 40 low-cost particulate matter (PM) monitors in Imperial County, California. Methods used to involve the community partner organization and residents in the development, operation, and use of the CAMN included the following: (1) establishing equitable partnerships among the project collaborators; (2) forming a community steering committee to guide project activities; (3) engaging residents in data collection to determine monitor sites; (4) providing hands-on training to assemble and operate the air monitors; (5) conducting focus groups to guide display and dissemination of monitoring data; and (6) conducting trainings on community action planning.

Contribution of low-cost sensor measurements to the prediction of PM levels: A case study in Imperial County, California, USA.

Regulatory monitoring networks are often too sparse to support community-scale PM exposure assessment while emerging low-cost sensors have the potential to fill in the gaps. To date, limited studies, if any, have been conducted to utilize low-cost sensor measurements to improve PM prediction with high spatiotemporal resolutions based on statistical models. Imperial County in California is an exemplary region with sparse Air Quality System (AQS) monitors and a community-operated low-cost network entitled Identifying Violations Affecting Neighborhoods (IVAN).

Next-Generation Community Air Quality Sensors for Identifying Air Pollution Episodes.

Conventional regulatory air quality monitoring sites tend to be sparsely located. The availability of lower-cost air pollution sensors, however, allows for their use in spatially dense community monitoring networks, which can be operated by various stakeholders, including concerned residents, organizations, academics, or government agencies. Networks of many community monitors have the potential to fill the spatial gaps between existing government-operated monitoring sites.

Is in utero exposure to maternal socioeconomic disadvantage related to offspring ovarian reserve in adulthood?

Background: Because the ovarian follicle pool is established in utero, adverse exposures during this period may be especially impactful on the size and health of the initial follicle endowment, potentially shaping trajectories of ovarian follicle loss and the eventual onset of menopause. Building on a robust literature linking socioeconomic status (SES) and menopausal timing, the current study examined adverse prenatal exposures related to maternal SES, hypothesizing that greater maternal socioeconomic disadvantage would be associated with lower ovarian reserve in the adult offspring.

Methods: In a healthy, community-based sub-sample ( = 350) of reproductive age participants in the OVA Study (2006-2011), prenatal maternal SES was examined in relation to two biomarkers of ovarian reserve, antimullerian hormone (AMH) and antral follicle count (AFC).

Residential agricultural pesticide exposures and risks of preeclampsia.

We investigated risks of preeclampsia phenotypes from potential residential pesticide exposures, including 543 individual chemicals and 69 physicochemical groupings that were applied in the San Joaquin Valley of California during the study period, 1998-2011. The study population was derived from birth certificate data linked with Office of Statewide Health Planning and Development maternal and infant hospital discharge data. The following numbers of women with preeclampsia phenotypes were identified: 1045 with superimposed (pre-existing hypertension with preeclampsia) preeclampsia (265 with gestational weeks 20-31 and 780 with gestational weeks 32-36); 3471 with severe preeclampsia (824 with gestational weeks 20-31 and 2647 with gestational weeks 32-36); and 2780 with mild preeclampsia (207 with gestational weeks 20-31 and 2573 with gestational weeks 32-36).

Combining Community Engagement and Scientific Approaches in Next-Generation Monitor Siting: The Case of the Imperial County Community Air Network.

Air pollution continues to be a global public health threat, and the expanding availability of small, low-cost air sensors has led to increased interest in both personal and crowd-sourced air monitoring. However, to date, few low-cost air monitoring networks have been developed with the scientific rigor or continuity needed to conduct public health surveillance and inform policy. In Imperial County, California, near the U.

Traffic-Related Air Pollution and All-Cause Mortality during Tuberculosis Treatment in California.

Background: Ambient air pollution and tuberculosis (TB) have an impact on public health worldwide, yet associations between the two remain uncertain.

Objective: We determined the impact of residential traffic on mortality during treatment of active TB.

Methods: From 2000-2012, we enrolled 32,875 patients in California with active TB and followed them throughout treatment.

Residential Agricultural Pesticide Exposures and Risks of Spontaneous Preterm Birth.

Background: Pesticides exposures are aspects of the human exposome that have not been sufficiently studied for their contribution to risk for preterm birth. We investigated risks of spontaneous preterm birth from potential residential exposures to 543 individual chemicals and 69 physicochemical groupings that were applied in the San Joaquin Valley of California during the study period, 1998-2011.

Methods: The study population was derived from birth certificate data linked with Office of Statewide Health Planning and Development maternal and infant hospital discharge data.

The Imperial County Community Air Monitoring Network: A Model for Community-based Environmental Monitoring for Public Health Action.

The Imperial County Community Air Monitoring Network (the Network) is a collaborative group of community, academic, nongovernmental, and government partners designed to fill the need for more detailed data on particulate matter in an area that often exceeds air quality standards. The Network employs a community-based environmental monitoring process in which the community and researchers have specific, well-defined roles as part of an equitable partnership that also includes shared decision-making to determine study direction, plan research protocols, and conduct project activities. The Network is currently producing real-time particulate matter data from 40 low-cost sensors throughout Imperial County, one of the largest community-based air networks in the United States.

Development and field validation of a community-engaged particulate matter air quality monitoring network in Imperial, California, USA.

Unlabelled: The Imperial County Community Air Monitoring Network was developed as part of a community-engaged research study to provide real-time particulate matter (PM) air quality information at a high spatial resolution in Imperial County, California. The network augmented the few existing regulatory monitors and increased monitoring near susceptible populations. Monitors were both calibrated and field validated, a key component of evaluating the quality of the data produced by the community monitoring network.

Evaluating the Use of Electronic Health Records for Type 2 Diabetes Surveillance in 2 California Counties, 2010-2014.

Objectives: Electronic health records (EHRs) and electronic laboratory records (ELRs) are increasingly seen as a rich source of data for performing public health surveillance activities and monitoring community health status. Their potential for surveillance of chronic illness, however, may be underused. Our objectives were to (1) evaluate the use of EHRs and ELRs for diabetes surveillance in 2 California counties and (2) examine disparities in diabetes prevalence by geography, income, and race/ethnicity.

Estimating the Proportion of Childhood Cancer Cases and Costs Attributable to the Environment in California.

Objectives: To estimate the proportion of cases and costs of the most common cancers among children aged 0 to 14 years (leukemia, lymphoma, and brain or central nervous system tumors) that were attributable to preventable environmental pollution in California in 2013.

Methods: We conducted a literature review to identify preventable environmental hazards associated with childhood cancer. We combined risk estimates with California-specific exposure prevalence estimates to calculate hazard-specific environmental attributable fractions (EAFs).

Heat Death Associations with the built environment, social vulnerability and their interactions with rising temperature.

In an extreme heat event, people can go to air-conditioned public facilities if residential air-conditioning is not available. Residences that heat slowly may also mitigate health effects, particularly in neighborhoods with social vulnerability. We explored the contributions of social vulnerability and these infrastructures to heat mortality in Maricopa County and whether these relationships are sensitive to temperature.

Analysis of multiple-variable missing-not-at-random survey data for child lead surveillance using NHANES.

Background: Although ongoing, multi-topic surveys form the basis of public health surveillance in many countries, their utility for specific subject matter areas can be limited by high proportions of missing data. For example, the National Health and Examination Survey is the main resource for surveillance of elevated blood lead levels (EBLLs) in US children, but key predictor variables are missing for as many as 35% of respondents.

Methods: Using a Bayesian framework, we formulate a t-distributed Heckman selection model applicable to the case of multiple missing-not-at-random variables in the context of a complex survey design.