Publications by authors named "Paul E Schwenn"

Various methods have been developed to combine inference across multiple sets of results for unsupervised clustering, within the ensemble clustering literature. The approach of reporting results from one 'best' model out of several candidate clustering models generally ignores the uncertainty that arises from model selection, and results in inferences that are sensitive to the particular model and parameters chosen. Bayesian model averaging (BMA) is a popular approach for combining results across multiple models that offers some attractive benefits in this setting, including probabilistic interpretation of the combined cluster structure and quantification of model-based uncertainty.

View Article and Find Full Text PDF

Cross-frequency coupling between the phase of slower oscillatory activity and the amplitude of faster oscillatory activity in the brain (phase-amplitude coupling; PAC), is a promising new biological marker for mental health. Prior research has demonstrated that PAC is associated with mental health. However, most research has focused on within-region theta-gamma PAC in adults.

View Article and Find Full Text PDF
Article Synopsis
  • The study aims to understand how brain activity is related to cognitive function and mental health risks in adolescents by identifying subgroups based on EEG data.
  • A multi-stage analysis was conducted on EEG recordings from 59 12-year-olds, using clustering algorithms to find distinct patterns of brain activity and their relation to mental health and cognitive function.
  • Five main subgroups were discovered, revealing significant differences in psychological distress, sleep quality, and cognitive performance, suggesting that analyzing these EEG patterns could improve risk prediction for mental health issues in adolescents.
View Article and Find Full Text PDF
Article Synopsis
  • Identifying biomarkers for mental disorders is crucial for improving early detection and treatment to reduce their overall impact.
  • Cross-frequency coupling (PAC) in brain oscillations shows promise for indicating cognitive processes and is linked to conditions like depression and schizophrenia.
  • Future longitudinal studies on PAC during adolescence could enhance our understanding of its relationship with mental health and inform new strategies for identification and treatment.
View Article and Find Full Text PDF