Publications by authors named "Paul D Hastings"

Background: Early and delayed puberty are both associated with adverse health and psychosocial outcomes.

Objectives: We assessed the impact of provision of small-quantity lipid-based nutrient supplement (SQ-LNS) to mothers during pregnancy and 6 mo postpartum and to their children aged 6-18 mo, on pubertal status.

Methods: This study was a follow-up to a partially double-blind randomized controlled trial.

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  • The study investigates how early-life lipid-based nutrient supplements (SQ-LNS) and home environment affect autonomic nervous system (ANS) regulation in children aged 9-11 years.
  • Participants included children from women in a Ghanaian trial where women received different nutritional supplements during pregnancy and postpartum.
  • Results show that those who received SQ-LNS or multiple micronutrients exhibited greater heart rate reactivity, while a better home environment was linked to more favorable ANS responses, indicating that early nutrition and the home setting play crucial roles in ANS development.
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  • Warm and supportive parenting is linked to better emotion regulation in children, but less is understood about its impact on adolescents, especially during a time when mental health issues often emerge.
  • The study focused on how maternal and paternal warmth from ages 10 to 16 affects adolescents' respiratory sinus arrhythmia (RSA), a measure related to emotion regulation, at age 17 in a sample of 229 Mexican-origin youths.
  • Results indicated that increases in maternal warmth during adolescence were connected to higher RSA in youths, suggesting that positive maternal interactions can enhance emotional regulation capabilities in teens.
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  • Childhood adversity (CA) is linked to higher risks of negative health outcomes, with differences in how various types of adversity affect brain structure during development.
  • Recent research indicates that deprivation leads to slower decreases in cortical surface area in certain brain regions, while threat exposure results in increased surface area in areas related to socio-emotional processing as adolescents age.
  • These findings suggest a need to reconsider how different forms of adversity affect brain development over time, highlighting the varying impacts on cognitive and emotional functions.
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  • Loneliness tends to increase as kids move from childhood into their teenage years, partly due to the body's natural stress response changes during puberty.
  • Different individuals react to stress in varying ways, leading some to withdraw socially ("fight-or-flight") and others to seek social support ("tend-and-befriend").
  • The authors suggest a model that explains these reactions and propose interventions aimed at improving social relationships, personality traits, and managing stress to reduce loneliness in adolescents.
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The significance of physiological regulation in relation to behavioral and emotional regulation is well documented, but primarily in economically advantaged contexts. Few studies have been conducted in low- and middle-income countries. We investigated the feasibility and reliability of measuring autonomic nervous system (ANS) activity and behavior during challenge tasks in 30 children aged 8-10 years in Ghana during two visits, 1 week apart.

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  • Both the parasympathetic nervous system and social support from family and friends play important roles in the development of prosocial behavior among adolescents, especially in racially and ethnically minoritized groups.
  • In a study involving 229 U.S. Mexican-origin adolescents, findings indicated that family support was linked to prosocial behavior at 17 years, while friend support influenced civic behavior at 19 years.
  • The research revealed that adolescents with moderate baseline respiratory sinus arrhythmia (RSA) showed higher cognitive empathy and prosocial behavior, highlighting the importance of both biological and social factors in fostering prosocial development.
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Despite copious data linking brain function with changes to social behavior and mental health, little is known about how puberty relates to brain functioning. We investigated the specificity of brain network connectivity associations with pubertal indices and age to inform neurodevelopmental models of adolescence. We examined how brain network connectivity during a peer evaluation fMRI task related to pubertal hormones (dehydroepiandrosterone and testosterone), pubertal timing and status, and age.

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Background: There is limited research on whether nutritional supplementation in the first 1000 d affects long-term child outcomes. We previously demonstrated that pre- and postnatal small-quantity lipid-based nutrient supplements (SQ-LNS) increased birth weight and child length at 18 mo of age in Ghana.

Objectives: We aimed to investigate the effect of pre- and postnatal SQ-LNS on child growth and blood pressure at 9-11 y.

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This study investigated specialized and versatile antisocial patterns in preschoolers and examined the link between these patterns and the risk of developing chronic antisocial behaviors throughout childhood. A total of 556 children (50.6% boys, 88% White) participated in this three-wave longitudinal study at 3-5, 6-8, and 10-12 years old.

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This two-year longitudinal study examined Mexican-origin adolescents' need to belong and cognitive reappraisal as predictors of multiple forms of prosocial behavior (i.e., general, emotional, and public prosocial behaviors).

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Early life adversity (ELA) characterized by threat (e.g., abuse, witnessing violence) impacts neural and physiologic systems involved in emotion reactivity; however, research on how threat exposure impacts the interplay between these systems is limited.

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  • SGM (sexual and gender minority) teens faced more challenges and difficulties in life than straight and cisgender youths even before COVID-19 hit.
  • During the pandemic, they dealt with extra stress, like being away from supportive friends and teachers and having to stay with families that might not accept them.
  • However, some SGM youths also found ways to handle the stress, like avoiding outside discrimination through remote learning and using their support systems.
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  • The study investigated how ethnic pride, familismo, and respeto influence positive youth development (PYD) in Mexican-origin adolescents in the U.S.
  • Researchers used a bifactor model to analyze the Five Cs of PYD—Caring, Character, Competence, Confidence, and Connection—establishing that this framework is stable over time from ages 14 to 16.
  • Findings revealed that a strong cultural orientation at age 14 positively influenced all aspects of PYD, with no differences based on gender or nativity, highlighting the significance of cultural factors in fostering youth development.
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Background: Provision of small-quantity lipid-based nutrient supplements (SQ-LNSs) during early life improves growth and development. In the International Lipid-Based Nutrient Supplements DYAD-Ghana trial, prenatal and postnatal SQ-LNS reduced social-emotional difficulties at age 5 y, with greater effects among children in less-enriched home environments.

Objectives: We aimed to investigate the effect of prenatal and postnatal SQ-LNS on children's social-emotional problems at age 9-11 y.

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  • There are two types of depression that can affect mothers: one before the baby is born (prenatal) and one after (postpartum), and they can both impact how kids think and learn.
  • This study looked at a lot of families in the UK to see how different periods of a mother's depression can affect her child’s brain development up to age 8.
  • It found that kids whose moms struggled with depression for a long time starting during pregnancy had the hardest time controlling their impulses and behaviors.
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Childhood adversity is a leading transdiagnostic risk factor for psychopathology, being associated with an estimated 31-62% of childhood-onset disorders and 23-42% of adult-onset disorders (Kessler et al., 2010). Major unresolved theoretical challenges stem from the nonspecific and probabilistic nature of the links between childhood adversity and psychopathology.

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  • The study explores the "p factor," a general liability for psychopathology, examining its link to executive functioning and affective regulation in adolescents with varying degrees of mental health issues.
  • Researchers used functional MRI while participants engaged in a task assessing sustained attention and inhibition, focusing on brain activation and behavioral responses.
  • Findings indicate that higher p factor scores correlate with poorer task performance and less brain activity in areas related to executive functioning, highlighting attention deficits as a common thread in different forms of mental disorders during adolescence.
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Alterations in immune system gene expression have been implicated in psychopathology, but it remains unclear whether similar associations occur for intraindividual variations in emotion. The present study examined whether positive emotion and negative emotion were related to expression of pro-inflammatory and antiviral genes in circulating leukocytes from a community sample of 90 adolescents (M = 16.3 years, SD = 0.

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There has been significant interest and progress in understanding the role of caregiver unpredictability on brain maturation, cognitive and socioemotional development, and psychopathology. Theoretical consensus has emerged about the unique influence of unpredictability in shaping children's experience, distinct from other adverse exposures or features of stress exposure. Nonetheless, the field still lacks theoretical and empirical common ground due to difficulties in accurately conceptualizing and measuring unpredictability in the caregiver-child relationship.

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