Interactive thyroid whole slide image diagnostic system using deep representation.

Background And Objectives: The vast size of the histopathology whole slide image poses formidable challenges to its automatic diagnosis. With the goal of computer-aided diagnosis and the insights that suspicious regions are generally easy to identify in thyroid whole slide images (WSIs), we develop an interactive whole slide diagnostic system for thyroid frozen sections based on the suspicious regions preselected by pathologists.

Methods: We propose to generate feature representations for the suspicious regions via extracting and fusing patch features using deep neural networks.

A Gaussian Mixture Model Representation of Endmember Variability in Hyperspectral Unmixing.

Hyperspectral unmixing while considering endmember variability is usually performed by the normal compositional model, where the endmembers for each pixel are assumed to be sampled from unimodal Gaussian distributions. However, in real applications, the distribution of a material is often not Gaussian. In this paper, we use Gaussian mixture models (GMM) to represent endmember variability.

A spatial compositional model for linear unmixing and endmember uncertainty estimation.

The normal compositional model (NCM) has been extensively used in hyperspectral unmixing. However, previous research has mostly focused on estimation of endmembers and/or their variability, based on the assumption that the pixels are independent random variables. In this paper, we show that this assumption does not hold if all the pixels are generated by a fixed endmember set.

Twenty years of mixture of experts.

In this paper, we provide a comprehensive survey of the mixture of experts (ME). We discuss the fundamental models for regression and classification and also their training with the expectation-maximization algorithm. We follow the discussion with improvements to the ME model and focus particularly on the mixtures of Gaussian process experts.