Publications by authors named "Paul Chinedu Echi"
Praziquantel (PZQ) is an acylated quinoline-pyrazine originally developed for veterinary application but now one of the most used anti-helminthic drugs for treatment of certain trematodes and cestodes in both human and other animals. The present study investigated the mutagenic and physiological responses in the juveniles of African catfish, Clarias gariepinus following short term exposure to praziquantel. Based on the 53.
View Article and Find Full Text PDFChanges in behavior and hematological parameters of freshwater African catfish Clarias gariepinus (Burchell 1822) following sublethal exposure to chloramphenicol.
Christopher Didigwu Nwani Blessing Nonye Mkpadobi Grace Onyishi Paul Chinedu Echi Christian Onyeka Chukwuka
Drug Chem Toxicol
January 2014
Article Synopsis
- The study investigated the effects of chloramphenicol (CAP), an antimicrobial drug, on the behavior and blood parameters of Clarias gariepinus fish exposed to varying concentrations (2.5, 5.0, and 10.0 mg/L).
- Higher concentrations of CAP led to observable abnormal behaviors in fish and significant changes in blood metrics, such as increased packed cell volume and decreased hemoglobin and mean cellular volume over time.
- Findings suggest that caution is necessary when using high concentrations of CAP for prolonged periods in aquaculture, as it impacts the fish's health significantly.