Epidemiology of norovirus infection in Nigeria: a systematic review and meta-analysis.

Human norovirus (HuNoV) is responsible for most cases of gastroenteritis worldwide, but information about the prevalence and diversity of HuNoV infections in lower-income settings is lacking. In order to provide more information about the burden and distribution of norovirus in Nigeria, we systematically reviewed original published research articles on the prevalence of HuNoV in Nigeria by accessing databases, including PubMed, Web of Science, ScienceDirect, Google Scholar, and African Journals Online (AJOL). The protocol for the review was registered on PROSPERO (registration number CRD42022308857).

Assessment of the aetiology of acute gastroenteritis outbreaks in infants reveals rotavirus, noroviruses and adenovirus prevalence and viral coinfections in Nsukka, Nigeria.

Unlabelled: A better understanding of the aetiology of acute gastroenteritis (AGE) outbreaks in Southeast Nigeria would help safeguarding public health. This study screened stool samples collected from infants (children < 5 years of age) attending selected hospitals in Nsukka for human enteric viruses and evaluated the seasonality of AGE based on three-year records available at selected hospitals. A total of 120 stool samples (109 from diarrhoeal-patients and 11 from non-diarrhoeal patients, as control) collected during the AGE outbreaks of January - March 2019 and January-February 2020.

Prevalence and relative risk of Rotavirus Gastroenteritis in children under five years in Nigeria: a systematic review and meta-analysis.

Rotavirus is responsible for most cases of gastroenteritis and mortality in children below 5 years of age, especially in developing countries, including Nigeria. Nonetheless, there is limited data on the nationwide estimate for the prevalence of rotavirus. This systematic review and meta-analysis sought to determine the pooled prevalence of rotavirus infections and its relative risk among children below 5 years of age in Nigeria.

Multi-locus sequence typing reveals genotypic similarity in Nigerian AFLP1/VNI of environmental and clinical origin.

Pigeon droppings are among the major environmental sources of AFLP1/VNI from where the organism infects susceptible humans and animals resulting in cryptococcosis. Until now, AFLP1B/VNII was the only molecular type reported in Nigeria. Effective clinical treatment of this infection has occasionally been stymied by the emergence of antifungal non-susceptible, and resistant strains of AFLP1/VNI.

The persistence of amoebosis caused by Entamoeba histolytica in Nigeria and the role of malnutrition.

Amoebosis, caused by the protozoan parasite Entamoeba histolytica is a gastrointestinal infection and the second leading cause of death from parasitic disease worldwide. The disease is endemic in many developing countries and kills over one hundred thousand persons annually. Adequate nutrition composed of macro- and micronutrients in their balanced proportions is central to effective gut immune response and the homeostasis of commensal organisms in the gastrointestinal tract.