Publications by authors named "Paul Chaillou"

Article Synopsis
  • Water-assisted laser desorption/ionization mass spectrometry (WALDI-MS), also known as SpiderMass, is a new method for analyzing biological samples in real-time using an infrared laser to excite water molecules.
  • The technique utilizes water as a natural matrix to help release and ionize various biomolecules, including metabolites and lipids, from tissue samples.
  • Recently, WALDI-MS has been developed into an imaging tool capable of producing both 2D and 3D images for ex vivo and in vivo studies, with specific guidelines for optimizing the imaging process.
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Mass spectrometry imaging (MSI) has shown to bring invaluable information for biological and clinical applications. However, conventional MSI is generally performed from tissue sections. Here, we developed a novel MS-based method for mass spectrometry imaging.

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