Publications by authors named "Paul Atangana"
Giant anogenital tumor of Buschke-Löwenstein in a patient living with human immunodeficiency virus/acquired immunodeficiency syndrome: a case report.
J Med Case Rep
March 2022
Article Synopsis
- Buschke-Löwenstein tumor is a rare but aggressive infection linked to HPV, often found in patients with HIV, characterized by large, ulcerated growths in the genital area.
- A case study highlighted a 21-year-old male with a significant tumor, multiple lesions, and co-infections of HIV and hepatitis B, which was diagnosed through biopsy.
- Treatment involved surgical intervention and antiviral therapy, but sadly, the patient's condition worsened due to an opportunistic infection, emphasizing the importance of regular screenings for other STIs in similar cases.
Article Synopsis
- Buruli ulcer (BU) is an infectious skin disease, and this study investigates its key histopathological features using 4-mm skin punch biopsies in Cameroon from 2011 to 2013.
- The study involved 364 patients with 422 lesions, identifying that out of 99 ulcerated lesions diagnosed as BU, histological analysis confirmed BU in 32, showing specific necrotic patterns and bacterial presence.
- The findings emphasize that punch biopsies are crucial for accurately diagnosing BU and differentiating it from other chronic ulcers, primarily characterized by subcutaneous necrosis and the detection of acid-fast bacilli.
Worldwide, the development of hepatocellular carcinoma (HCC) is known to be influenced by several hepatitis B viral factors. However, the effect of hepatitis B virus (HBV) genotypes and a landscape of nucleotide changes affecting the precore (PC) and basal core promoter (BCP) during infection leading to HCC remain largely unknown in the Central Africa region. Thus, we performed a case-control study on patients with HBV-related HCC and matched controls without HCC but with chronic HBV infection.
View Article and Find Full Text PDFObjective: This study evaluates the occurrence of the various morphological subtypes of hepatocellular carcinoma (HCC) and their connections with some risk factors in Cameroonian patients. The database of the 360 liver biopsies received and associated medical records were reviewed for histological and demographic analysis. Archival formalin-fixed and paraffin embedded liver biopsy specimens or slide were re-evaluated in malignancies patients.
View Article and Find Full Text PDFHepatocellular carcinoma (HCC) is still a major killing malignancy in sub-Saharan Africa. Lifelong intoxication with aflatoxin B1 is considered as one of the primary causes of this situation. The role of aflatoxin in HCC from a given population is commonly estimated through the prevalence of R249S mutation of TP53, a hallmark for previous exposure to the mycotoxin.
View Article and Find Full Text PDFPurpose: To report the case of infestation of the eyelashes presenting as chronic blepharoconjunctivitis.
Case Report: A 6-year-old girl presented with a 2-month history of blepharoconjunctivitis unresponsive to topical antibiotics in the left eye. Slit-lamp examination revealed the presence of nits and adult parasites on the eyelashes.
Background: Ocular contusion can produce severe lesions, which if not treated appropriately and promptly, can lead to visual impairment. Ocular contusion in childhood may not be reported by children.
Case Presentation: A 27 year old female presented with a partially absorbed cataractous lens that was dislocated into the anterior chamber of her left eye.
Objectives: To determine the seroprevalence of hepatitis E virus (HEV) infection in patients with chronic hepatitis and/or hepatocellular carcinoma (HCC) and to assess its potential consequences for disease progression.
Methods: We conducted a prospective case-control study on patients with HCC hepatitis B or C related and non-HCC patients including patients with CLD and patients without clinical evidence of liver disease. Anti-HEV IgG and IgM were tested by ELISA using commercially available kits.
Background: Clinical diagnosis of Buruli ulcer (BU) due to Mycobacterium ulcerans can be challenging. We aimed to specify the differential diagnosis of skin lesions in a BU endemic area.
Method: We conducted a prospective diagnostic study in Akonolinga, Cameroon.
Leishmaniasis is a disease caused by a protozoan parasite of the genus leishmania with worldwide distribution and is transmitted to man by phlebotomine sand flies. The clinical presentation could range from a single cutaneous ulcer to disseminated leishmaniasis. We report the case of a four-year-old boy admitted to our hospital with ulcers, wasting, progressively distending abdomen, and fatigue evolving for about two months.
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