The aphrodisiac herb Carpolobia: A biopharmacological and phytochemical review.

Any agent with the ability to provoke sexual desire in an individual is referred to as an aphrodisiac. Aphrodisiac plants are used in the management of erectile dysfunction (ED) in men. One such plant popular in West and Central Africa among the Pygmies of Cameroon, Ipassa of Garbon, and the Yoruba, Ibo, Efik and Ijaw peoples of Nigeria is Carpolobia.

In vivo antiplasmodial potentials of the combinations of four nigerian antimalarial plants.

Various combinations of Nauclea latifolia root, Artocarpus altilis stem bark, Murraya koenigii leaf and Enantia chlorantha stem bark used in African ethnomedicine as decoctions for malaria and fevers, and combinations with standard drugs, were investigated for antiplasmodial activities using Plasmodium berghei berghei-infected mice. The respective prophylactic and curative ED50 values of 189.4 and 174.

Antioxidative burst and hepatoprotective effects of ethanol root extract of Hippocratea africana against paracetamol-induced liver injury.

Context: Hippocratea africana (Willd.) Loes. ex Engl.

Antimicrobial activity of Carpolobia lutea extracts and fractions.

Carpolobia lutea (G. Don) (Polygalaceae) is a tropical medicinal plant putative in traditional medicines against gonorrhea, gingivitis, infertility, antiulcer and malaria. The present study evaluated the antimicrobial, antifungal and antihelicobacter effects of extracts C.

Nephroprotective effect of Croton zambesicus root extract against gentimicin-induced kidney injury.

Objective: To evaluate the kidney protective effect of ethanolic root extract of Croton zambesicus (C. zambesicus) against gentimicin-induced kidney injury in rats.

Methods: The root extract (27-81 mg/kg) was administered to rats for eight days with concurrent administration of gentimicin (100 mg/kg) daily for the same period of time.

Contraceptive, estrogenic and anti-estrogenic potentials of methanolic root extract of Carpolobia lutea in rodents.

Several plants are used in herbal medicine for family planning. Carpolobia lutea is a medicinal plant in South Eastern Nigeria used for family planning. The study was designed to investigate the contraceptive, estrogenic and antiestrogenic potentials of the methanolic root extract of Carpolobia lutea in both rats and mice.

Antidiarrheal mechanism of Carpolobia lutea leaf fractions in rats.

Context: Carpolobia lutea G. Don (Polygalaceae) leaf is reputable as an antidiarrheal agent among the Efik and Ibibio tribe of Akwa Ibom State, Nigeria. The crude extract is reported to show antidiarrheal and antiulcer effects in rodents.

Antimalarial and analgesic activities of ethanolic leaf extract of Panicum maximum.

Objective: To evaluate antiplasmodial and analgesic activities of ethanolic leaf extract/fractions of Panicum maximum.

Methods: The crude leaf extract (47-190 mg/kg) and fractions (chloroform, ethyl acqeous and methanol; 96 mg/kg) of Panicum maximum were investigated for antiplasmodial activity against chloroquine sensitive Plasmodium berghei infections in mice and for analgesic activity against chemical and heat-induced pains. The antiplasmodial activity during early and established infections as well as prophylactic were investigated.

Anti-nociceptive effects of Carpolobia lutea G. Don (Polygalaceae) leaf fractions in animal models.

Leaves from Carpolobia lutea (Polygalaceae) were screened to establish the antiulcer ethnomedicinal claim and to quantitatively isolate, elucidate the active compounds by semi-preparative HPLC. The anti-nociceptive effects of Carpolobia lutea (CL) G. Don (Polygalaceae) organic leaf extracts were tested in experimental models in mice.

Antiinflammatory, analgesic and antipyretic activities of ethanolic root extract of Croton zambesicus.

The ethanolic root extract of C. zambesicus (27-81mg/kg) was evaluated for antiiflammatory, analgesic and antipyretic properties in mice. The extract (27-81mg/kg) demonstrated a weak antiinflammatory activity.

Subchronic toxicity studies of the ethanolic root extract of Croton zambesicus.

Subchronic toxicity study of the crude root extract of Croton zambesicus (27-81 mg/kg), which is used traditionally as malarial remedy, was carried out in rodents to evaluate the safety profile. Effect of the extract on body weights, haematological indices as well as liver and kidney functions and histology of various organs were investigated. Subchronic treatment of rats for 21 days caused comparable increase in body weights of rats in extract treated and control groups.

Antimicrobial activity of root extract and crude fractions of Croton zambesicus.

The root extract and fractions of Croton zambesicus were screened for antimicrobial activity against some typed and pure cultures of bacterial and fungal species. These were carried out by the Plate-hole diffusion method on Mueller-Hinton agar (MHA) for bacteria and Sabouraud Dextrose Agar (SDA) for the fungi. The Minimum Inhibitory Concentrations (MICs) of test samples found to be active by the diffusion test were determined based on the macrodilution method.

Analgesic and antimalarial activities of crude leaf extract and fractions of Acalypha wilkensiana.

Aim Of The Study: Antiplasmodial and analgesic activities of leaf extract and fractions of Acalypha wilkensiana were evaluated to ascertain the folkloric claim of its antimalarial and analgesic activities.

Materials And Methods: The crude leaf extract (220-659 mg/kg) and fractions (chloroform and aqueous; 440 mg/kg) of Acalypha wilkensiana were investigated for antiplasmodial activity against chloroquine sensitive Plasmodium berghei infections in mice and for analgesic activity against chemical and heat-induced pains. The antiplasmodial activity during early and established infections as well as prophylactic activity were investigated.

Antiulcer and anticonvulsant activity of Croton zambesicus.

The ethanolic root extract of Croton zambesicus was investigated for its potential to protect gastric mucosa against ulcers induced by indomethacin, ethanol and reserpine. The anticonvulsant activity of the root extract against pentylene tetrazol (PTZ)- and picrotoxin-induced convulsion in mice was also studied. The extract (27-81 mg/kg) produced a significant (P<0.

Antiplasmodial activity of root extract and fractions of Croton zambesicus.

Aim Of The Study: Antiplasmodial activity of root extract and fractions of Croton zambesicus were evaluated to ascertain the folkloric claim of its antimalarial activity and elucidate its antiplasmodial mechanism of action.

Material And Method: The crude ethanolic root extract (27-81 mg/kg) and gradient fractions (n- hexane, chloroform, ethyl acetate and methanol; 54 mg/kg) of Croton zambesicus were investigated for antiplasmodial activity against chloroquine--sensitive Plasmodium berghei infections in mice. The antiplasmodial activity during early and established infections as well as the prophylactic activity were investigated.

Effects of methanolic extract of Asparagus pubescens root on sexual behavior and pituitary hormone secretion on Wistar rats during pregnancy and lactation.

We investigated the effect of methanolic extract of Asparagus pubescens root on sexual behavior and on pituitary hormone secretion during pregnancy and lactation on Wistar rats. Different doses (0.25, 0.

Evaluation of anti-diarrhoeal and anti-ulcerogenic potential of ethanol extract of Carpolobia lutea leaves in rodents.

The effect of ethanol extract of Carpolobia lutea leaves on experimentally induced diarrhoea and ulcers was studied in rodents. The extract (245-735 mg/kg) inhibited small intestinal transit time (15.10-45.

Anti-nociceptive and anti-inflammatory effects of methanolic extract of Asparagus pubescens root in rodents.

The effect of methanolic extract of Asparagus pubescens was investigated on chemical, thermal-induced pain as well as fresh egg albumin-induced inflammation and pentylenetetrazol (PTZ)-induced convulsion in rodents. The extract dose-dependently (0.25-1.