Publications by authors named "Pau Lluis Gozalbo Sabater"
Tissue microarray profiling of primary and xenotransplanted synovial sarcomas demonstrates the immunophenotypic similarities existing between SYT-SSX fusion gene confirmed, biphasic, and monophasic fibrous variants.
Manish Mani Subramaniam Samuel Navarro Antonio Pellin Jose Antonio López-Guerrero Carmen Carda Pau Lluís Gozalbo Sabater
Virchows Arch
October 2006
Article Synopsis
- The paper explores the diversity of synovial sarcomas (SSs), focusing on biphasic, monophasic fibrous, and poorly differentiated types, and their evaluation through tissue microarrays (TMAs) in a xenograft model.
- Findings indicate that biphasic and monophasic fibrous synovial sarcomas exhibit a progression to a similar undifferentiated phenotype in xenografts, with notable expressions of certain proteins like bcl-2 and contribution to high mitotic indices.
- Hierarchical clustering analysis suggests phenotypic variability among original tumors, but similarities in immunoexpression profiles in xenografts, while confirming genetic stability through detection of SYT-SSX transcripts in all