Safety and effectiveness of a modification of diet in renal disease equation-based potassium replacement protocol.

Background: No data exist regarding the safety and effectiveness of a potassium replacement protocol for hospitalized patients when potassium replacement dosing regimens (KRDRs) are adjusted to Modification of Diet in Renal Disease estimation of glomerular filtration rate (MDRD GFR).

Objective: To evaluate the effectiveness and safety of a potassium replacement protocol in which KRDRs are prescribed based on MDRD GFR and serum potassium deficiency (Kdef).

Methods: Patients prescribed the potassium replacement order set were identified in a retrospective fashion.