Canadian national survey of point-of-care ultrasound training in family medicine residency programs.

Objective: To assess the current state of point-of-care ultrasound (POCUS) training in Canadian family medicine residency programs.

Design: Cross-sectional survey to evaluate POCUS education in accredited Canadian family medicine residency programs; only 1 completed survey was accepted per residency program.

Setting: Seventeen accredited Canadian family medicine residency programs.

Needs assessment for development of 6for6: Longitudinal research skills program tailored to rural and remote family physicians.

Problem Addressed: Rural and remote family physicians (RRFPs) face greater barriers to research engagement than their urban colleagues and have access to fewer faculty development programs (FDPs) to foster their research skills.

Objective Of Program: To identify and prioritize skills and services that RRFPs need to engage in research.

Program Description: Memorial University of Newfoundland in St John's used a needs assessment as the foundation for developing an FDP for RRFPs.

Curriculum development of 6for6: Longitudinal research skills program for rural and remote family physicians.

Problem Addressed: To address barriers challenging the engagement of rural and remote family physicians (RRFPs) in research, Memorial University of Newfoundland in St John's has developed a longitudinal faculty development program (FDP) called 6for6.

Objective Of Program: To establish and evaluate a longitudinal FDP that promotes a foundation of research activity. Program description Informed by a needs assessment in phase 1, phase 2 saw the 6for6 curriculum designed, developed, and implemented to reflect the unique needs of RRFPs.

Protein expression pattern of human MIER1 alpha, a novel estrogen receptor binding protein.

MIER1 is a transcriptional regulator that exists as several isoforms. Of particular interest is the MIER1α isoform, which contains in its unique C-terminus an LXXLL motif for interaction with nuclear hormone receptors. Indeed, MIER1α has been shown to interact with ERα and inhibit estrogen-stimulated growth of breast carcinoma cells.

Protein expression of the transcriptional regulator MI-ER1 alpha in adult mouse tissues.

MI-ER1 is a novel transcriptional regulator that plays a critical role in embryonic development and is differentially expressed in breast carcinoma. The MI-ER1 protein sequence is highly conserved among species, with 95% identity between mouse and humans and 72% between Xenopus and mouse. There are two major protein isoforms, MI-ER1alpha and MI-ER1beta, which differ in the sequence of their C-terminus.