FFAs and QT intervals in obese women with visceral adiposity: effects of sustained weight loss over 1 year.

We evaluated 66 obese patients grouped by waist-to-hip ratio (WHR) into group A (WHR > 0.85, n = 30) and group B (WHR < or = 0.85, n = 36), before and after 1 yr of diet-induced weight loss compared with 25 nonobese women.

Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year.

Background: Visceral fat is a key regulator site for the process of inflammation, and atherosclerotic lesions are essentially an inflammatory response.

Methods And Results: Fifty-six healthy premenopausal obese women (age range 25 to 44 years, body mass index 37.2+/-2.