Publications by authors named "Patrizia Birarelli"
Article Synopsis
- - This study investigates how surgery affects the immune cells, specifically lymphocytes, in pancreatic cancer patients over time, looking closely at changes before and after duodenopancreatectomy.
- - Results showed that while natural killer (NK) cells increased and B-cells decreased 30 days post-surgery, there was a temporary drop in NK cell activity 7 days after the procedure, indicating a short-term impairment.
- - The findings suggest that while surgery initially disrupts NK cell function, it may eventually boost their numbers and help restore normal behavior, which could improve the body’s ability to fight leftover cancer cells.
Malignant mesothelioma (MM) is a tumor with local invasive behaviour. Tenascin-C (TN-C) with fibronectin (FN) are associated extracellular matrix (ECM) molecules frequently neo-expressed in stromal remodeling during neoplastic progression, mostly at the invasive edge of these tumors. Tenascin-C alone or in association with other ECM molecules, could play an important role in the process of tumor invasion, acting as substrate for movement or modulating the migration on FN or promoting the degradation of ECM.
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