Publications by authors named "Patrick Yizhi Cai"

Article Synopsis
  • Branched DNA molecules play a critical role in DNA processes like replication and repair, making their structural understanding essential for grasping these biological mechanisms.
  • While gel electrophoresis offers a bulk analysis of DNA, direct visualization at the single-molecule level is necessary but requires pure samples free from unwanted DNA interference.
  • The study focuses on overcoming challenges in isolating large, branched DNA structures, specifically in E. coli, by utilizing techniques like β-agarase digestion and multiple rounds of gel electrophoresis for enhanced sample purity.
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