Using an Assumed Lung Mass Inaccurately Estimates the Lung Absorbed Dose in Patients Undergoing Hepatic Yttrium Radioembolization Therapy.

Rationale: Currently, the estimated absorbed radiation dose to the lung in Y radioembolization therapy is calculated using an assumed 1 kg lung mass for all patients. The aim of this study was to evaluate whether using a patient-specific lung mass measurement for each patient rather than a generic, assumed 1 kg lung mass would change the estimated lung absorbed dose.

Methods: A retrospective analysis was performed on 68 patients who had undergone Y radioembolization therapy at our institution.

PET imaging of hepatocellular carcinoma with anti-1-amino-3-[F]fluorocyclobutanecarboxylic acid in comparison with L-[S-methyl-C]methionine.

Purpose: [C]methionine ([C]Met) was used for cancer imaging based on upregulated amino acid transport and protein synthesis in different tumor types. However, the short half-life of C decay limited further clinical development of [C]Met. Synthetic amino acid analog anti-1-amino-3-[F]fluoro-cyclobutyl-1-carboxylic acid ([F]FCABC) was developed and FDA-approved for PET imaging of recurrent prostate cancer.

The impact of orthopedic metal artifact reduction software on interreader variability when delineating areas of interest in the head and neck.

Purpose: Metal artifacts during computed tomography (CT) hinder the evaluation of diagnostic images and impair the delineation of tumor volume in treatment planning. Several solutions are available to minimize these artifacts. Our objective was to determine the impact of one of those tools on the interreader variability when measuring head and neck structures in the presence of metal artifacts.

Image quality assessment of automatic three-segment MR attenuation correction vs. CT attenuation correction.

The purpose of this study is to systematically evaluate the usefulness of Positron emission tomography/Magnetic resonance imaging (PET/MRI) images in a clinical setting by assessing the image quality of Positron emission tomography (PET) images using a three-segment MR attenuation correction (MRAC) versus the standard CT attenuation correction (CTAC). We prospectively studied 48 patients who had their clinically scheduled FDG-PET/CT followed by an FDG-PET/MRI. Three nuclear radiologists evaluated the image quality of CTAC vs.