Expanding Naloxone Coprescribing at a Regional VA Medical Center.

Veterans are disproportionately affected by chronic pain and are more likely to be prescribed opioids. As a means of risk mitigation, the Centers for Disease Control and Prevention and Department of Defense recommend naloxone for patients on opioids with risk factors, including use of ≥50 morphine milligram equivalents daily, concurrent benzodiazepine/sedative use, and pulmonary or liver disease. An interprofessional quality improvement team consisting of 6 residents, a pharmacist, a nurse educator, and a faculty mentor was formed to increase naloxone coprescriptions at a regional VA medical center Continuity of Care Clinic.

Gestalt contexture and contested motives: Understanding video evidence in the murder trial of Officer Michael Slager.

This article is situated in ongoing discussions about the influx of images of police violence. To date, much scholarship has centred on Foucauldian notions of knowledge-power and . Alternatively, I attend to how video evidence produces understanding of police violence in court through a case study of the murder trial of Officer Michael Slager who shot and killed Walter Scott in North Charleston, South Carolina.

Use of Thromboelastography and Rotational Thromboelastometry in Otolaryngology: A Narrative Review.

In the field of otolaryngology-head and neck surgery (ENT), coagulopathies present unique diagnostic and therapeutic challenges. In both hyper- and hypocoagulable patients, management of coagulopathies requires intricate attention to the nature of hemostatic competence. Common coagulation tests (CCTs) offer only a snapshot of hemostatic competence and do not provide a clear insight into the patient's real-time hemostatic condition.

An accelerating crisis: Metascience is out-reproducing psychological science.

Scientific claims are selected in part for their ability to survive. Scientists can pursue an r-strategy of broad, easy-to-spread ideas, or a K-strategy of stress-tested, bulletproof statements. The "generalizability crisis" is an exquisite mutation that allows dull, K-strategic methodology articles to spread nearly as quickly as the fast-breeding, r-strategic memes of pop-psychology.

Structural and Functional MRI Evidence for Distinct Medial Temporal and Prefrontal Roles in Context-dependent Relational Memory.

Declarative memory is supported by distributed brain networks in which the medial-temporal lobes (MTLs) and pFC serve as important hubs. Identifying the unique and shared contributions of these regions to successful memory performance is an active area of research, and a growing literature suggests that these structures often work together to support declarative memory. Here, we present data from a context-dependent relational memory task in which participants learned that individuals belonged in a single room in each of two buildings.

Aging affects spatial reconstruction more than spatial pattern separation performance even after extended practice.

Although the hippocampus experiences age-related anatomical and functional deterioration, the effects of aging vary across hippocampal-dependent cognitive processes. In particular, whether or not the hippocampus is known to be required for a spatial memory process is not an accurate predictor on its own of whether aging will affect performance. Therefore, the primary objective of this study was to compare the effects of healthy aging on a test of spatial pattern separation and a test of spatial relational processing, which are two aspects of spatial memory that uniquely emphasize the use of multiple hippocampal-dependent processes.

Relational memory and self-efficacy measures reveal distinct profiles of subjective memory concerns in older adults.

Objective: Subjective memory concerns (SMCs) in healthy older adults are associated with future decline and can indicate preclinical dementia. However, SMCs may be multiply determined, and often correlate with affective or psychosocial variables rather than with performance on memory tests. Our objective was to identify sensitive and selective methods to disentangle the underlying causes of SMCs.

Competition and Cooperation among Relational Memory Representations.

Mnemonic processing engages multiple systems that cooperate and compete to support task performance. Exploring these systems' interaction requires memory tasks that produce rich data with multiple patterns of performance sensitive to different processing sub-components. Here we present a novel context-dependent relational memory paradigm designed to engage multiple learning and memory systems.

Cognitive neuroscience of human counterfactual reasoning.

Counterfactual reasoning is a hallmark of human thought, enabling the capacity to shift from perceiving the immediate environment to an alternative, imagined perspective. Mental representations of counterfactual possibilities (e.g.

The role of the hippocampus in flexible cognition and social behavior.

Successful behavior requires actively acquiring and representing information about the environment and people, and manipulating and using those acquired representations flexibly to optimally act in and on the world. The frontal lobes have figured prominently in most accounts of flexible or goal-directed behavior, as evidenced by often-reported behavioral inflexibility in individuals with frontal lobe dysfunction. Here, we propose that the hippocampus also plays a critical role by forming and reconstructing relational memory representations that underlie flexible cognition and social behavior.

Relating hippocampus to relational memory processing across domains and delays.

The hippocampus has been implicated in a diverse set of cognitive domains and paradigms, including cognitive mapping, long-term memory, and relational memory, at long or short study-test intervals. Despite the diversity of these areas, their association with the hippocampus may rely on an underlying commonality of relational memory processing shared among them. Most studies assess hippocampal memory within just one of these domains, making it difficult to know whether these paradigms all assess a similar underlying cognitive construct tied to the hippocampus.

Spatial reconstruction by patients with hippocampal damage is dominated by relational memory errors.

Hippocampal damage causes profound yet circumscribed memory impairment across diverse stimulus types and testing formats. Here, within a single test format involving a single class of stimuli, we identified different performance errors to better characterize the specifics of the underlying deficit. The task involved study and reconstruction of object arrays across brief retention intervals.

War-making and sense-making: some technical reflections on an instance of 'friendly fire'.

In this paper we analyse a 'friendly fire' incident from the second Gulf War and the controversy which came to envelop it during a coroner's inquest in 2007. Focusing on the cockpit video of the incident that was leaked to the media during that inquest, we examine what the military and civilian investigators were involved in reconstructing: the incident as it unfolded in real time. Our analysis is grounded in a praxeological perspective that draws on and links ethnomethodological studies of work, research into 'normal' accidents, disasters and risks, and recent ethnographies of the military.