Morphologic and functional changes in nontumorous liver tissue after radiofrequency ablation in an in vivo model: comparison of 18F-FDG PET/CT, MRI, ultrasound, and CT.

Unlabelled: Rimlike contrast enhancement on morphologic imaging and increased tracer uptake on (18)F-FDG PET in the periphery of the necrosis can hamper differentiation of residual tumor from regenerative tissue after radiofrequency ablation of liver lesions. This study used MRI, CT, ultrasound, and (18)F-FDG PET/CT to assess the typical appearance of lesions in nontumorous animal liver tissue after radiofrequency ablation.

Methods: Lesions were created by radiofrequency ablation of normal liver parenchyma in 21 minipigs.

[Leydig cell tumor as a cause of hirsutism in a postmenopausal woman].

Background: Hirsutism or virilization in postmenopausal women may be due to increased testosterone levels caused by an androgen-secreting tumor. The preoperative localization of small ovarian or adrenal androgen-secreting tumors is difficult.

Case Report: A 61-year-old, postmenopausal woman presented with progressive hirsutism and deepening of voice over the last 9 years.

Can PET/CT replace separate diagnostic CT for cancer imaging? Optimizing CT protocols for imaging cancers of the chest and abdomen.

Stage-adapted treatment in oncology relies on correct tumor staging for patients with malignant diseases. To ensure accurate assessment of the tumor stage in thoracic and abdominal diseases by PET/CT, both CT and PET need to be optimized. In this setting, different malignant diseases require customized imaging protocols.

Accuracy of combined PET/CT in image-guided interventions of liver lesions: an ex-vivo study.

Aim: Positioning of interventional devices in liver lesions is a challenging task if only CT is available. We investigated the potential benefit of combined PET/CT images for localization of interventional devices in interventional liver studies.

Methods: Thirty lesions each of hyperdense, isodense and hypodense attenuation compared to normal liver parenchyma were injected into 15 ex-vivo pig livers.

Lymph node staging with dual-modality PET/CT: enhancing the diagnostic accuracy in oncology.

Lymph node staging according to the TNM criteria is an essential part of tumor evaluation. Several morphological and functional imaging procedures are used complementarily in this setting. Dual-modality PET/CT scanners are able to provide anatomical and functional data sets in a single session with accurate image co-registration.

Evaluation of integrated whole-body PET/CT in the detection of recurrent ovarian cancer.

Purpose: To assess the usefulness and reliability of integrated whole-body positron emission tomography/computed tomography (PET/CT) in patients in whom recurrent ovarian cancer is suspected.

Methods: Integrated whole-body PET/CT imaging was performed in 19 patients with suspected ovarian cancer recurrence. CT, PET and fused PET/CT images were evaluated separately and imaging results were compared with pathological findings and clinical follow-up after 6 months.

Contrast-enhanced dark lumen PET/CT and MR colonography in a rodent polyp model: initial results with histopathologic correlation.

Objective: The objective of this study was to assess the feasibility of PET/CT for the detection of colorectal masses in a rodent polyp model in an intraindividual comparison with dark-lumen MR colonography.

Conclusion: Detection of small tumors with PET/CT and MR colonography is possible in a rodent model. The technique thus warrants further evaluation in animal studies as well as in patients with suspected colorectal disease.

Respiration artifacts in whole-body (18)F-FDG PET/CT studies with combined PET/CT tomographs employing spiral CT technology with 1 to 16 detector rows.

Purpose: Co-registration accuracy in combined whole-body (WB) PET/CT imaging is impaired by respiration-induced mismatches between the CT and the PET. Furthermore, PET/CT misregistration may bias the PET tracer distribution following CT-based attenuation correction (CT-AC). With the introduction of multi-row CT technology of up to 16 detector rows into PET/CT designs, we investigated the incidence of respiration artifacts in WB PET/CT examinations of patients who were unable to follow any breath-hold instructions.

Positron emission tomography/computed tomography improves diagnostics of inflammatory arteritis.

Based on the unique property of fluorine-18 fluorodeoxyglucose, localization and follow-up of hypermetabolic processes is possible with positron emission tomography (PET). The dual-modality PET/computed tomography (CT) systems provide intrinsically fused morphologic and functional data in a single examination. We report on two patients with inflammatory aortitis and positive PET/CT findings.

Digital subtraction dark-lumen MR colonography: initial experience.

Purpose: To evaluate image subtraction for the detection of colonic pathologies in a dark-lumen MR colonography exam.

Materials And Methods: A total of 20 patients (12 males; 8 females; mean 51.4 years of age) underwent MR colonography after standard cleansing and a rectal water enema on a 1.

Detection of residual tumor after radiofrequency ablation of liver metastasis with dual-modality PET/CT: initial results.

The aim of this study was to determine the accuracy of dual-modality positron emission tomography(PET)/computed tomography (CT) in the detection of residual tumor after radiofrequency ablation (RFA) of liver metastasis of colorectal cancer. Eleven patients with 16 hepatic metastases (mean size 2.9 cm) from colorectal cancer were enrolled in this study, and 19 RFA procedures and 32 PET/CT examinations were performed.

Assessment of liver tissue after radiofrequency ablation: findings with different imaging procedures.

Unlabelled: Our goal was to assess the typical appearance of normal liver tissue immediately after radiofrequency ablation (RF-ablation) when imaged with contrast-enhanced ultrasound, CT, MRI, 18F-FDG PET, and PET/CT.

Methods: Nineteen RF-ablation sessions were performed on nontumorous liver tissue of 10 Göttingen Mini Pigs. CT, ultrasound, MRI, 18F-FDG PET, and PET/CT were performed immediately after the intervention.

Diagnostic accuracy of time-resolved 2D projection MR angiography for symptomatic infrapopliteal arterial occlusive disease.

Objective: Our objective was to evaluate the diagnostic accuracy of time-resolved 2D projection MR angiography in detecting calf and pedal artery occlusive disease.

Materials And Methods: Time-resolved MR angiography of calf and pedal arteries was performed on 59 symptomatic legs of 52 patients using the head coil and bolus injections of 6 mL of gadolinium contrast medium. Selective X-ray digital subtraction angiography was performed within 30 days after MR angiography.

Optimization of contrast dosage for gadobenate dimeglumine-enhanced high-resolution whole-body 3D magnetic resonance angiography.

Rationale And Objectives: To determine the optimal dose of gadobenate dimeglumine for diagnostic high-resolution whole-body 3D-MR angiography.

Methods: Ten healthy volunteers were examined three times with an ascending dose of Gd-BOPTA (0.1/0.