Synopsis of recent research by authors named "Patrick T Orr"
- Patrick T. Orr's research primarily investigates the neurobiological mechanisms of memory formation and how hormones, specifically estradiol and progesterone, influence memory processes, particularly in the context of object recognition tasks in mice.
- His studies highlight the role of signaling pathways such as mTOR, ERK, and PI3K in the hippocampus, demonstrating that these pathways are critical for memory consolidation following hormonal treatments, which could have implications for understanding memory deficits related to developmental or hormonal changes.
- Additionally, Orr's work has explored the cognitive and behavioral phenotypes associated with genetic deletions, such as the 16p11.2 deletion, indicating a broader interest in neurodevelopmental outcomes and their relation to behavioral and cognitive functions.
