Publications by authors named "Patrick Strasser"

The amount of C in steel, which is critical in determining its properties, is strongly influenced by steel production technology. We propose a novel method of quantifying the bulk C content in steel non-destructively using muons. This revolutionary method may be used not only in the quality control of steel in production, but also in analyzing precious steel archaeological artifacts.

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  • Interleukins are proteins that help regulate the immune system, with the IL-12 family being important in dealing with inflammatory and infectious diseases.
  • IL-35, a less understood member of this family, is crucial in autoimmune diseases and cancer but is distinct as it comprises two subunits, IL-12α and EBI3.
  • The study shows that these subunits can promote their own secretion, act independently as anti-inflammatory agents, lower proinflammatory cytokines, and help develop regulatory T cells, suggesting new avenues for immunotherapies.
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Objective: Climate change constitutes a major challenge. The higher education sector plays an important role in regard to climate change and the adaptation to its consequences. Various approaches toward the integration of environmental subject areas to higher education teaching have already been described in other studies, but there is a lack of data supporting the effectiveness of these approaches in changing not only the environmental knowledge of students, but also their awareness.

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  • Cancer stem cells (CSCs) are key players in tumor recurrence and metastasis, arising from complex epithelial-mesenchymal transitions (EMTs) that create diverse cell states.
  • The study successfully isolated pure populations of human breast CSCs using the cell-surface marker integrin β4 (ITGB4) and characterized the underlying gene regulatory network.
  • It highlights the role of transcription factors ΔNp63 and p73 in regulating quasi-mesenchymal CSCs, revealing that their activity resembles a regenerative response to injury rather than normal stem cell functions, which promotes cancer spread through autocrine EGFR signaling.
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Introduction: Global warming is one of the major challenges faced by society. To raise students' awareness related to these issues, we embedded environmental learning goals in mandatory courses. The aim of this initiative was to determine whether the integration of environmental topics into a seminar focussing on non-environmental issues facilitates changes in the environmental knowledge and awareness of students.

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On-site teaching at Ulm University was restricted in the summer semester (SS) 2020 due to the Corona pandemic. The biochemistry seminar "From gene to protein" in the 2nd preclinical semester, which had been successfully conducted as an Inverted Classroom (IC), had to be changed to an online concept. The aim of this study was to analyze the concept conversion in terms of students' satisfaction and knowledge acquisition.

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Elemental analysis of materials is fundamentally important to science and technology. Many elemental analysis methods have been developed, but three-dimensional nondestructive elemental analysis of bulk materials has remained elusive. Recently, our project team, dreamX (damageless and regioselective elemental analysis with muonic X-rays), developed a nondestructive depth-profiling elemental analysis method after a decade of research.

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