Radiofrequency (RF) ablation is a recently developed technique for image-guided local destruction of selected tumors. Because the lung is a common site for cancer and usually has substantial functional reserve, RF ablation of lung cancers is an attractive option for minimally invasive treatment. The primary goal of the present review is to describe the natural history, staging systems, and conventional therapies for primary and secondary treatment of lung cancer, as well as the results of RF ablation in animal models and in humans for pulmonary applications, to clarify the appropriate role and limitations of this technology.
View Article and Find Full Text PDFInterventional radiology (IR) plays an increasing role in the supportive care of the cancer patient from the placement of catheters to treating the offending tumor via image-guided methods. These methods entail the use of both local and regional means, with thermal ablative technology comprising the former and intra-arterial embolization with radioactive particles the latter. Direct placement of the radiofrequency or cryotherapy probes into tumors that are accessible using computed tomography (CT), ultrasound, or magnetic resonance imaging (MRI) guidance provides reliable symptomatic relief of single or multiple tumors in liver, kidney, lung, bone, or soft tissue.
View Article and Find Full Text PDFA case of multiple hepatic adenomas associated with birth control pills in a 25-year-old female is presented. Her only complaint was abdominal pain, and an elevated alkaline phosphatase was the only laboratory abnormality. The largest adenoma was located in the caudate lobe and was resected.
View Article and Find Full Text PDFBackground: The lung is the most common site for primary cancer worldwide as well as being a common site of metastases for various malignancies. Percutaneous radiofrequency ablation (RFA) is rapidly evolving as a new minimally invasive tool for the treatment of pulmonary tumors.
Patients And Methods: A questionnaire was sent by e-mail to 14 centres around the world, which we knew or thought were performing percutaneous pulmonary RFA, to retrospectively survey their experience in this field including the number of ablations done to date, indications, method, peri- and postprocedural complications.
Radiofrequency (RF) thermal ablation has shown promise as a technique for treating inoperable solid tumors involving the liver, kidney, adrenal gland, and lung. However, like all other imaging-guided interventional procedures, RF ablation involves some element of risk. Varying degrees of complications can be expected, depending on factors such as the organ site and the aggressiveness of the procedure.
View Article and Find Full Text PDFWe describe the first two cases of percutaneous cryoablation under magnetic resonance imaging guidance. To date, this minimally invasive procedure has been used for the treatment of renal cell tumors in patients who cannot tolerate or refuse surgical nephrectomy. The two patients described showed no evidence of recurrence or complications 35 and 36 months after the procedure.
View Article and Find Full Text PDFPurpose: To determine the effect of cryoablation on the collecting system in the porcine kidney and the possible development of pelvic injury or fistula.
Materials And Methods: Six kidneys from three domestic swine were utilized. Under MRI guidance, a 3-mm cryoprobe was placed percutaneously and advanced to a point adjacent to the collecting system.
Objective: The purpose of this study was to identify alternatives to hysterectomy. We have developed a transabdominal interventional magnetic resonance imaging-guided cryoablation procedure and report this novel approach.
Study Design: This represents the preliminary and first report of a prospective Institutional Review Board-approved protocol to study interventional magnetic resonance imaging-guided cryoablation of uterine fibroid tumors.
Radiofrequency ablation is a new investigational therapy for primary and secondary neoplasms. In this article, the authors describe the anesthetic management of the radiofrequency ablation of a pulmonary neoplasm complicated by massive hemorrhage.
View Article and Find Full Text PDFPurpose: We determine the feasibility and safety of performing percutaneous cryoablation of renal tumors in patients with von Hippel-Lindau disease.
Materials And Methods: We selected 2 men and 2 women with von Hippel-Lindau disease and radiographic determined solid renal tumors were selected to undergo percutaneous cryoablation. All patients underwent standard preoperative evaluation.