Longitudinal and Cross-sectional Analyses of Lung Function in Toluene Diisocyanate Production Workers.

Objective: The aim of this study was to investigate lung function among toluene diisocyanate (TDI) production workers.

Methods: One hundred ninety-seven U.S workers performed spirometry from 2006 through 2012.

Incidence of Occupational Asthma and Exposure to Toluene Diisocyanate in the United States Toluene Diisocyanate Production Industry.

Objective: This study examines asthma risk in facilities producing toluene diisocyanate (TDI).

Methods: A total of 197 workers were monitored from 2007 to 2012. TDI air concentrations were used to estimate exposures.

Medical Monitoring for Occupational Asthma Among Toluene Diisocyanate Production Workers in the United States.

Objective: The aim of this study was to describe a study of medical monitoring methods and lessons learned in detecting health outcomes in U.S. plants producing toluene diisocyanate (TDI).

Developing a registry of workers involved in nanotechnology: BASF experiences.

Objective: To assist BASF in the establishment of a registry of workers involved in nanotechnology.

Methods: The initial step was a complete inventory of nanomaterials and sites of use. Guidance was developed to clarify which particulate nanomaterials were to be included in the survey.

Investigation of cancer occurrences associated with an herbicide manufacturing facility.

This study evaluated cancer incidence and mortality among 251 employees of a facility that synthesized a benzothiadiazin herbicide between 1979-1987. It was initiated in response to a perceived cancer cluster. Cancers were identified mainly by review of occupational medical records and personal interviews.

Experience with early detection of toluene diisocyanate-associated occupational asthma.

There is good reason to expect that regular respiratory surveillance and early removal of workers who develop toluene diisocyanate (TDI)-associated occupational asthma can effectively protect these workers from accelerated pulmonary function decline. Application of this simple principle in operating industrial workplaces presents numerous challenges. The experience of one corporation is presented.