3D virtual histopathology of cardiac tissue from Covid-19 patients based on phase-contrast X-ray tomography.

For the first time, we have used phase-contrast X-ray tomography to characterize the three-dimensional (3d) structure of cardiac tissue from patients who succumbed to Covid-19. By extending conventional histopathological examination by a third dimension, the delicate pathological changes of the vascular system of severe Covid-19 progressions can be analyzed, fully quantified and compared to other types of viral myocarditis and controls. To this end, cardiac samples with a cross-section of 3.

Real-Time Volumetric Synthetic Aperture Software Beamforming of Row-Column Probe Data.

Two delay-and-sum beamformers for 3-D synthetic aperture imaging with row-column addressed arrays are presented. Both beamformers are software implementations for graphics processing unit (GPU) execution with dynamic apodizations and third-order polynomial subsample interpolation. The first beamformer was written in the MATLAB programming language and the second was written in C/C++ with the compute unified device architecture (CUDA) extensions by NVIDIA.