Publications by authors named "Patrick L Maher"

Background: Peripheral nerve and infraclavicular brachial plexus injury following proximal humerus fractures are commonplace, but diagnosing a concomitant nerve injury in the acute setting is challenging. Fracture displacement has been identified as a qualitative risk factor for nerve injury, and additional attention should be paid to the neurologic exams of patients with proximal humerus fractures with significant medial shaft displacement. However, a quantitative relationship between the risk of nerve injury and medialization of the humeral shaft has not been shown, and additional risk factors for this complication have not been assessed.

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Staphylococcus aureus is a common organism in orthopedic infections, but little is known about the genetic diversity of strains during an infectious process. Using periprosthetic joint infection (PJI) as a model, a prospective study was designed to quantify genetic variation among S. aureus strains both among and within patients.

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Article Synopsis
  • This study aimed to create a rabbit model to better understand chronic periprosthetic joint infections (PJIs), which are difficult to treat.
  • The researchers injected bacteria into the rabbits' bone and monitored changes in inflammation and bone health over 28 days.
  • Results showed that the introduction of bacteria led to significant inflammation and bone damage, confirming that this model can be used for future treatment research on PJIs.
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